IL-27 Found to Play Significant Role in Conferring HIV Resistance

Portrait of Lue Dai.

Lue Dai, Ph.D., postdoctoral fellow, Laboratory of Human Retrovirology, Applied and Developmental Research Directorate, SAIC-Frederick.

Platinum Highlight IconBy Nancy Parrish, Staff Writer

The human immunodeficiency virus (HIV) targets specific immune cells in the body known as macrophages because these are the cells that eliminate foreign material such as bacteria or viruses. HIV is able to reproduce and spread throughout the body if it can avoid destruction by macrophages.

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$200,000 Grants Awarded to CCR Researchers for HIV/AIDS Studies

Anu Puri and team

Anu Puri, Ph.D., left, and her team are developing a drug delivery system that uses targeted nanoparticles containing FDA-approved anti-HIV-1 drugs. Shown with Puri are, from left: Weizao Chen, Ph.D., Dimiter Dimitrov, Ph.D., and Robert Blumenthal, Ph.D. Inset: Sanjay Malhotra, Ph.D. Their work is in collaboration with Rinti Banerjee, Ph.D., at the Indian Institute of Technology Bombay, Mumbai, India.

By Nancy Parrish, Staff Writer

Earlier this year, the Office of AIDS Research (OAR) awarded two, two-year grants of $200,000 each to Anu Puri, Ph.D., and Robert Blumenthal, Ph.D., both of the Center for Cancer Research (CCR) Nanobiology Program, and to Eric Freed, Ph.D., of the HIV Drug Resistance Program, for their research on potential new treatments for HIV.

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Best Collaborative Publication Announced during Spring Research Festival Week

Two gentlemen having a discussion

Kamal Saikh, Ph.D., left, and David Waugh, Ph.D., were winners of the 2012 competition for best collaborative publication among NICBR partners.

By Nancy Parrish, Staff Writer

The winner of the 2012 competition for the best collaborative publication was announced on May 7, as part of the lead-up to the Spring Research Festival sponsored by the National Interagency Confederation for Biological Research (NICBR) and the National Cancer Institute at Frederick on May 8 and 9.

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FNLCR Set to Launch Full-Scale Assault on Ras

Ribbon structure

H-Ras structure PDB 121p ribbon showing strands in purple, helices in aqua, and loops in gray. Also shown are the bound GTP analog and magnesium ion. Image from Wikipedia, https://en.wikipedia.org/wiki/Ras_subfamily

By Frank Blanchard, Staff Writer

Armed with an array of leading-edge technologies, scientific and technical expertise, and the full backing of the National Cancer Institute’s (NCI’s) scientific advisers, the Frederick National Laboratory for Cancer Research (FNLCR) is preparing to launch a full-scale attack against an intractable problem:  the cancer-causing family of Ras genes.

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Digging Up Local History

Archaeological dig lecture

Volunteers listen to archaeologist Roy Brown discuss how to haft a rock by attaching a bone or stick to a rock, making a tool. Brown’s talk was one of the lunchtime lectures held during the dig. Photo courtesy of Susie Culler.

By Carolynne Keenan, Contributing Writer

In the beginning weeks of summer, Recreation and Welfare (R&W) Club Frederick members experienced a once-in-a-lifetime activity: an archaeological dig in Walkersville, alongside Charlie Hall, Ph.D., Maryland state terrestrial archaeologist.

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Green Team Recognized with HHS Green Champion Award Honorable Mention

Members of the Green Team

Several members of the NCI at Frederick Green Team holding their HHS Green Champion Award honorable mention certificates. Back row, from left, Dolores Winterstein, Melissa Porter, Denise Shelley, and Cheryl Bowman. Front row, from left, Linda Brandenburg and Eckart Bindewald. Not pictured: Thomas Schneider, Howard Young, and former members Chelsey Jahn and Melissa Lambert.

Courtesy of the NCI at Frederick Green Team

The NCI at Frederick Green Team received a Department of Health and Human Services (HHS) Green Champion Award honorable mention in June for the team’s plant swap initiative, begun in October 2012. 

“The Green Team has been doing a great job this past year, and it is wonderful that their efforts have been recognized by the HHS through the Green Champion Awards,” said Craig Reynolds, Ph.D., director of the NCI Office of Scientific Operations (OSO). 

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