A Really Great Speech That Almost Wasn’t

By Ken Michaels, Guest Writer

As the anniversary of the birth of the Rev. Dr. Martin Luther King Jr. approaches, I’m reminded of two other, equally noteworthy, events that have special meaning to aficionados of excellence in speechifying. And they are especially significant to those in our geographical area; both occurred within 50 miles of Frederick, Md.                                    

The first event occurred on Aug. 28, 1963, when King delivered a speech in front of the Lincoln Memorial during the celebrated March on Washington for Jobs and Freedom demonstration. The other event was 100 years earlier, on Nov. 19, 1863.

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NCI Scientists Awarded National Medal of Technology and Innovation by President Obama

Two NCI scientists received the National Medal of Technology and Innovation, the nation’s highest honor for technological achievement. The award was announced by President Obama in October. The honorees, John Schiller, Ph.D., Laboratory of Cellular Oncology (LCO), Center for Cancer Research, NCI, and Douglas Lowy, M.D., also from LCO and NCI deputy director, received their medals at a White House ceremony on Nov. 20.

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Platinum Publications as of November 26, 2014

Platinum Publications are selected from articles by NCI at Frederick scientists published in 42 prestigious science journals. This list represents new publications generated from PubMed as of the date shown above.

Articles designated as Platinum Highlights are noteworthy articles selected by Dr. Craig Reynolds, associate director, National Cancer Institute, from among the most recently published Platinum Publications.

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Interaction between EphrinB1 and CNK1 Found to Play Role in Tumor Progression

Two scientists in the lab. Doctor Cho is on left and Doctor Daar is on right.

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By Nancy Parrish, Staff Writer

The family of proteins known as ephrins plays a critical role in a variety of biological processes. In a recent article in the Journal of Biological Chemistry, Hee Jun Cho, Ph.D., and colleagues report on the interaction between proteins CNK1 and ephrinB1 that promotes cell movement. Their findings may have an important implication in developing new therapeutics for reducing metastases in certain cancers.

“Eph and ephrin signaling has become an area of intense interest due to the influence these molecules exert on the control of cell adhesion and cell movement,” Cho said. “This signaling affects the formation of tissues during development and has been shown to play an instructive role in angiogenesis, as well as tumor cell invasion.”

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