Platinum Publications – As of December 3, 2013

Platinum Publications graphic

Platinum Publications are selected from articles by NCI at Frederick scientists published in 21 prestigious science journals. This list represents new publications generated from PubMed as of the date shown above.

Articles designated as Platinum Highlights are noteworthy articles selected by Dr. Craig Reynolds, associate director, National Cancer Institute, from among the most recently published Platinum Publications.

The Scientific Library maintains the NCI-Frederick-in-Print database, a collection of citations for journal articles authored by NCI at Frederick employees since 1997.

Platinum highlight

denotes Platinum Highlight article. Click on the image to go to the Platinum Highlight article.

 


 

”Blood

Blood

Astermark J, Donfield SM, et al. The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort. Blood 121(8):1446-1454, 2013.

Haso, W, DW Lee, et al. Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia. Blood 121(7):1165-1174, 2013.

Klion AD, Mejia R, et al. Chronic active Epstein-Barr virus infection: a novel cause of lymphocytic variant hypereosinophilic syndrome. Blood 121(12):2364-2366, 2013.

Kuehn HS, Niemela JE, et al. Loss-of-function of the protein kinase C delta (PKC delta) causes a B-cell lymphoproliferative syndrome in humans. Blood 121(16):3117-3125, 2013.

Purdue MP, Hofmann JN, et al. A prospective study of 67 serum immune and inflammation markers and risk of non-Hodgkin lymphoma. Blood 122(6):951-957, 2013.

Tinsley KW, Hong CW, Luckey MA, Park JY, Kim GY, Yoon HW, Keller HR, Sacks AJ, Feigenbaum L, Park JH. Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus. Blood 122(14):2358-2368, 2013.

Unnisa, Z, JP Clark, et al. Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress. Blood 120(25):4973-4981, 2012.

Waldmann, TA, KC Conlon, et al. Phase 1 trial of IL-15 trans presentation blockade using humanized Mik-Beta-1 mAb in patients with T-cell large granular lymphocytic leukemia. Blood 121(3):476-484, 2013.

Wolfl M, Schwinn S, et al. Src-kinase inhibitors sensitize human cells of myeloid origin to Toll-like-receptor-induced interleukin 12 synthesis. Blood 122(7):1203-1213, 2013.

 

”Cancer

Cancer Research

Aggarwal M, Banerjee T, Sommers JA, Iannascoli C, Pichierri P, Shoemaker RH, Brosh RM. Werner syndrome helicase has a critical role in DNA damage responses in the absence of a functional Fanconi Anemia pathway. Cancer Res 73(17):5497-5507, 2013.

Garcia-Closas, M, N Rothman, et al. Common genetic polymorphisms modify the effect of smoking on absolute risk of bladder cancer. Cancer Res 73(7):2211-2220, 2013. http://cancerres.aacrjournals.org/con-tent/73/7/2211.long Ittmann M, Huang J, et al. Animal models of human prostate cancer: The Consensus Report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee. Cancer Res 73(9):2718-2736, 2013.

Liu, Y, KQ Chen, et al. Cell surface receptor FPR2 promotes antitumor host defense by limiting M2 polarization of macrophages. Cancer Res 73(2):550-560, 2013. http://cancerres.aacrjournals.org/content/73/2/550.long Marino N, Marshall JC, Collins JW, Zhou M, Qian YZ, Veenstra T, Steeg PS. Nm23-H1 binds to gelsolin and inactivates its actin-severing capacity to promote tumor cell motility and metastasis. Cancer Res 73(19):5949-5962, 2013.

Saud SM, Young MR, Jones-Hall YL, Ileva L, Evbuomwan MO, Wise J, Colburn NH, Kim YS, Bobe G. Chemopreventive Activity of Plant Flavonoid Isorhamnetin in Colorectal Cancer Is Mediated by Oncogenic Src and beta-Catenin. Cancer Res 73(17):5473-5484, 2013.

Zhu, Z Q, V Singh, et al. High-avidity T cells are preferentially tolerized in the tumor microenvironment. Cancer Res 73(2):595-604, 2013.

 

”Cell

Cell

Fang X, Wang J, O’Carroll IP, Mitchell M, Zuo X, Wang Y, Yu P, Liu Y, Rausch JW, Dyba MA, Kjems J, Schwieters CD, Seifert S, Winans RE, Watts NR, Stahl SJ, Wingfield PT, Byrd RA, Le Grice SF, Rein A, Wang YX. An unusual topological structure of the HIV-1 Rev response element. Cell 155(3):594-605, 2013.

Lauberth, SM, T Nakayama, et al. H3K4me3 interactions with TAF3 regulate preinitiation complex assembly and selective gene activation. Cell 152(5):1021-1036, 2013.

Lee NN, Chalamcharla VR, Reyes-Turcu F, Mehta S, Zofall M, Balachandran V, Dhakshnamoorthy J, Taneja N, Yamanaka S, Zhou M, Grewal SIS. Mtr4-like protein coordinates nuclear RNA processing for heterochromatin assembly and for telomere maintenance. Cell 155(5):1061-1074, 2013.

Nussinov R, Tsai CJ. Allostery in disease and in drug discovery. Cell 153(2):293-305, 2013.

Van Laethem F, Tikhonova AN, Pobezinsky LA, Tai XG, Kimura MY, Le Saout C, Guinter TI, Adams A, Sharrow SO, Bernhardt G, Feigenbaum L, Singer A. Lck availability during thymic selection determines the recognition specificity of the T cell repertoire. Cell 154(6):1326-1341, 2013.

 

JACS

Journal of the American Chemical Society

Dong, SW, T Qin, et al. Synthesis of chamaecypanone C analogues from in situ-generated cyclopentadienones and their biological evaluation. J Amer Chem Soc 134(48):19782-19787, 2012.

 

JBC

Journal of Biological Chemistry

Chen KQ, Liu MY, et al. Signal relay by CC chemokine receptor 2 (CCR2) and formylpeptide receptor 2 (Fpr2) in the recruitment of monocyte-derived dendritic cells in allergic airway inflammation. J Biol Chem 288(23):16262-16273, 2013.

Platinum highlightChertova E, Bergamaschi C, et al. Characterization and favorable in vivo properties of heterodimeric soluble IL-15 center dot IL-15R alpha cytokine compared to IL-15 monomer. J Biol Chem 288(25):18093- 18103, 2013.

Chung S, Miller JT, et al. Examining the role of the HIV-1 reverse transcriptase p51 subunit in positioning and hydrolysis of RNA/DNA hybrids. J Biol Chem 288(22):16177-16184, 2013.

Hatanaka, T, S Ohzono, et al. Human IgA-binding peptides selected from random peptide libraries affinity maturation and application in IgA purification. J Biol Chem 287(51):43126-43136, 2012.

Jalah, R, M Rosati, et al. The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit implications for improved IL-12 cytokine production. J Biol Chem 288(9):6763-6776, 2013.

Madenspacher, JH, KM Azzam, et al. Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity. J Biol Chem 287(52):43730-43740, 2012.

Oguariri RM, Dai L, et al. Interleukin-2 inhibits HIV-1 replication in some human t cell lymphotrophic virus-1-infected cell lines via the induction and incorporation of APOBEC3G into the virion. J Biol Chem 288(24):17812-17822, 2013.

Patki M, Chari V, et al. The ETS domain transcription factor ELK1 directs a critical component of growth signaling by the androgen receptor in prostate cancer cells. J Biol Chem 288(16):11047-11065, 2013.

Singh A, Winterbottom EF, et al. Abelson interactor 1 (Abi1) and its interaction with Wiskott-Aldrich syndrome protein (Wasp) are critical for proper eye formation in xenopus embryos. J Biol Chem 288(20):14135- 14146, 2013.

Strathern, J, F Malagon, et al. The fidelity of transcription RPB1 (RPO21) mutations that increase transcriptional slippage in S. cerevisiae. J Biol Chem 288(4):2689-2699, 2013.

Tsutsui Y, Ramakrishnan B, Qasba PK. Crystal structures of beta-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding. J Biol Chem 288(44):31963-31970, 2013.

Wei H, Bera TK, et al. A modified form of diphthamide causes immunotoxin resistance in a lymphoma cell line with a deletion of the WDR85 gene. J Biol Chem 288(17):12305- 12312, 2013.

Platinum highlight

Ying T, Chen W, Feng Y, Wang Y, Gong R, Dimitrov DS. Engineered soluble monomeric IgG1 CH3 domain: generation, mechanisms of function, and implications for design of biological therapeutics. J Biol Chem 288(35):25154-25164, 2013.

Zhang SF, Schones DE, et al. High mobility group protein N5 (HMGN5) and lamina-associated polypeptide 2 alpha (LAP2 alpha) interact and reciprocally affect their genome-wide chromatin organization. J Biol Chem 288(25):18104-18109, 2013.

Zhou, YN, L Lubkowska, et al. Isolation and characterization of RNA polymerase rpoB mutations that alter transcription slippage during elongation in Escherichia coli. J Biol Chem 288(4):2700-2710, 2013.

 

”Journal

Journal of Clinical Investigation

Chen KD, Liu MY, et al. Formylpeptide receptor-2 contributes to colonic epithelial homeostasis, inflammation, and tumorigenesis. J Clin Invest 123(4):1694-1704, 2013.

Horn, HF, Z Brownstein, et al. The LINC complex is essential for hearing. J Clin Invest 123(2):740-750, 2013.

Klatt, NR, LA Canary, et al. Probiotic/ prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques. J Clin Invest 123(2):903- 907, 2013.

Onnis B, Fer N, et al. Autocrine production of IL-11 mediates tumorigenicity in hypoxic cancer cells. J Clin Invest 123(4):1615-1629, 2013.

Stewart CA, Metheny H, Iida N, Smith L, Hanson M, Steinhagen F, Leighty RM, Roers A, Karp CL, Muller W, Trinchieri G. Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation. J Clin Invest 123(11):4859-4874, 2013.

Xi, SC, H Xu, et al. Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis. J Clin Invest 123(3):1241-1261, 2013.

 

”Journal

Journal of Experimental Medicine

Bouchlaka MN, Sckisel GD, Chen MY, Mirsoian A, Zamora AE, Maverakis E, Wilkins DEC, Alderson KL, Hsiao HH, Weiss JM, Monjazeb AM, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Redelman D, Taub DD, Murphy WJ. Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy. J Exp Med 210(11):2223-2237, 2013.

Platinum highlightDai, L, KB Lidie, et al. IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation. J Exp Med 210(3):517-34, 2013.

Hasan UA, Zannetti C, et al. The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the toll-like receptor 9 promoter. J Exp Med 210(7):1369-1387, 2013.

Kiviranta R, Yamana K, et al. Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages. J Exp Med 210(5):969-985, 2013.

Singh SK, Williams CA, et al. Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance. J Exp Med 210(5):987-1001, 2013.

 

Journal of Immunology

Journal of Immunology

Alvarez M, Sungur CM, et al. Contrasting effects of anti-Ly49A due to MHC class I cis binding on nk cell-mediated allogeneic bone marrow cell resistance. J Immunol 191(2):688-698, 2013.

Canary, LA, CL Vinton, et al. Rate of AIDS progression is associated with gastrointestinal dysfunction in simian immunodeficiency virus-infected pigtail macaques. J Immunol 190(6):2959-2965, 2013.

Chen, X, XQ Wu, et al. TNFR2 is critical for the stabilization of the CD4(+)Foxp3(+) regulatory t cell phenotype in the inflammatory environment. J Immunol 190(3):1076- 1084, 2013.

Dauphinee SM, Clayton A, et al. SASH1 is a scaffold molecule in endothelial TLR4 signaling. J Immunol 191(2):892-901, 2013.

Kaminski JJ, Schattgen SA, Tzeng TC, Bode C, Klinman DM, Fitzgerald KA. Synthetic oligodeoxynucleotides containing suppressive TTAGGG motifs inhibit AIM2 inflammasome activation. J Immunol 191(7):3876-3883, 2013.

Kobayashi, N, CM Hong, et al. Oligodeoxynucleotides expressing polyguanosine motifs promote antitumor activity through the upregulation of IL-2. J Immunol 190(4):1882- 1889, 2013.

Park H, Adamson L, et al. Polyinosinic-polycytidylic acid is the most effective TLR adjuvant for SIV gag protein-induced t cell responses in nonhuman primates. J Immunol 190(8):4103-4115, 2013.

Shenderov K, Barber DL, et al. Cord factor and peptidoglycan recapitulate the Th17- promoting adjuvant activity of mycobacteria through Mincle/CARD9 signaling and the inflammasome. J Immunol 190(11):5722- 5730, 2013.

Shi GP, Vistica BP, et al. Differential involvement of Th1 and Th17 in pathogenic autoimmune processes triggered by different TLR ligands. J Immunol 191(1):415- 423, 2013.

Schreiner J, Kretschmer D, et al. Staphylococcus aureus phenol-soluble modulin peptides modulate dendritic cell functions and increase in vitro priming of regulatory T cells. J Immunol 190(7):3417-3426, 2013.

Tewary P, de la Rosa G, et al. beta-defensin 2 and 3 promote the uptake of self or CpG DNA, enhance IFN-alpha production by human plasmacytoid dendritic cells, and promote inflammation. J Immunol 191(2):865- 874, 2013.

Wu, YZ, JM Lu, et al. Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-gamma and lipopolysaccharide in human pancreatic cancer cell lines. J Immunol 190(4):1859-1872, 2013.

 

JNCI

Journal of the National Cancer Institute

Kohaar, I, P Porter-Gill, et al. Genetic variant as a selection marker for antiprostate stem cell antigen immunotherapy of bladder cancer. J Natl Cancer Inst 105(1):69-73, 2013.

Shiels MS, Pfeiffer RM, Hildesheim A, Engels EA, Kemp TJ, Park JH, Katki HA, Koshiol J, Shelton G, Caporaso NE, Pinto LA, Chaturvedi AK. Circulating inflammation markers and prospective risk of lung cancer. J Natl Cancer Inst 2013. [Epub ahead of print. This article is not yet available in the print journal.]

Xu, H, W Yang, et al. Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. J Natl Cancer Inst 2013.

 

MCB

Molecular and Cellular Biology

Huggins CJ, Malik R, et al. C/EBPgamma suppresses senescence and inflammatory gene expression by heterodimerizing with C/EBPbeta. Mol Cell Biol 33(16):3242-58, 2013.

 

Nature

Nature

Burns, MB, L Lackey, et al. APOBEC3B is an enzymatic source of mutation in breast cancer. Nature 494(7437):366-370, 2013.

Creighton CJ, Morgan M, et al. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature 499(7456):43-49, 2013.

Hansen SG, Piatak M, Ventura AB, Hughes CM, Gilbride RM, Ford JC, Oswald K, Shoemaker R, Li Y, Lewis MS, Gilliam AN, Xu GW, Whizin N, Burwitz BJ, Planer SL, Turner JM, Legasse AW, Axthelm MK, Nelson JA, Fruh K, Sacha JB, Estes JD, Keele BF, Edlefsen PT, Lifson JD, Picker LJ. Immune clearance of highly pathogenic SIV infection. Nature 502(7469):100-104, 2013.

Lammermann T, Afonso PV, et al. Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo. Nature 498(7454):371-+, 2013.

McShane LM, Cavenagh MM, Lively TG, Eberhard DA, Bigbee WL, Williams PM, Mesirov JP, Polley MYC, Kim KY, Tricoli JV, Taylor JMG, Shuman DJ, Simon RM, Doroshow JH, Conley BA. Criteria for the use of omics-based predictors in clinical trials. Nature 502(7471):317-320, 2013.

Mudd, PA, MA Martins, et al. Vaccine-induced CD8(+) t cells control AIDS virus replication. Nature 491(7422):129-U152, 2012.

Roederer M, Keele BF, Schmidt SD, Mason RD, Welles HC, Fischer W, Labranche C, Foulds KE, Louder MK, Yang ZY, Todd JP, Buzby AP, Mach LV, Shen L, Seaton KE, Ward BM, Bailer RT, Gottardo R, Gu W, Ferrari G, Alam SM, Denny TN, Montefiori DC, Tomaras GD, Korber BT, Nason MC, Seder RA, Koup RA, Letvin NL, Rao SS, Nabel GJ, Mascola JR. Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV. Nature 2013. [Epub ahead of print.]

Shingai M, Nishimura Y, Klein F, Mouquet H, Donau OK, Plishka R, Buckler-White A, Seaman M, Piatak M, Lifson JD, Dimitrov DS, Nussenzweig MC, Martin MA. Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia. Nature 503(7475):277-280, 2013.

 

Nature Cell Biology

Das A, Tanigawa S, Karner CM, Xin M, Lum L, Chen C, Olson EN, Perantoni AO, Carroll TJ. Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation. Nat Cell Biol 15(9):1035-1044, 2013.

 

Nature Genetics

Nature Genetics

Berndt SI, Gustafsson S, et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 45(5):501-U69, 2013.

Chung CC, Kanetsky PA, et al. Meta-analysis identifies four new loci associated with testicular germ cell tumor. Nat Genet 45(6):680-+, 2013.

Eeles RA, Al Olama AA, et al. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet 45(4):385-391, 2013.

Lonsdale J, Thomas J, et al. The genotype-tissue expression (GTEx) project. Nat Genet 45(6):580-585, 2013.

Monda KL, Chen GK, et al. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet 45(6):690-+, 2013.

Savage SA, Mirabello L, et al. Genome-wide association study identifies two susceptibility loci for osteosarcoma. Nat Genet 45(7):799-+, 2013.

 

Nature Immunology

Cella M, Trinchieri G. A new VEGF connection between two old neighbors. Nat Immunol 15(1):8-9, 2013.

Jelicic K, Cimbro R, Nawaz F, Huang DW, Zheng X, Yang J, Lempicki RA, Pascuccio M, Van Ryk D, Schwing C, Hiatt J, Okwara N, Wei DL, Roby G, David A, Hwang IY, Kehrl JH, Arthos J, Cicala C, Fauci AS. The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-beta 1 production and FcRL4 expression. Nat Immunol 14(12):1256-1265, 2013.

 

Nature Medicine

Nature Medicine

Cubas RA, Mudd JC, et al. Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nat Med 19(4):494-+, 2013.

Lucas D, Scheiermann C, et al. Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration. Nat Med 19(6):695-+, 2013.

Ranasinghe S, Cutler S, et al. Association of HLA-DRB1-restricted CD4(+) T cell responses with HIV immune control. Nat Med 19(7):930-+, 2013.

Wang X, Zhao YJ, et al. Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down’s syndrome. Nat Med 19(4):473-+, 2013.

 

New England Journal of Medicine

Persaud D, Gay H, Ziemniak C, Chen YH, Piatak M, Chun TW, Strain M, Richman D, Luzuriaga K. Absence of Detectable HIV-1 Viremia after Treatment Cessation in an Infant. N Engl J Med 369(19):1828-1835, 2013.

 

Oncogene

Oncogene

Aprelikova O, Palla J, et al. Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility. Oncogene 32(27):3246- 3253, 2013.

Hudson RS, Yi M, et al. MicroRNA- 106b-25 cluster expression is associated with early disease recurrence and targets caspase-7 and focal adhesion in human prostate cancer. Oncogene 32(35):4139-4147, 2013.

Kang Z, Yu Y, Zhu YJ, Davis S, Walker R, Meltzer PS, Helman LJ, Cao L. Downregulation of IGFBP2 is associated with resistance to IGF1R therapy in rhabdomyosarcoma. Oncogene 2013. [Epub ahead of print. This article is not yet available in the print journal.]

Liu, YN, JJ Yin, et al. MiR-1 and miR-200 inhibit EMT via slug-dependent and tumorigenesis via slug-independent mechanisms. Oncogene 32(3):296-306, 2013.

Tang Y, Horikawa I, et al. Downregulation of splicing factor SRSF3 induces p53 beta, an alternatively spliced isoform of p53 that promotes cellular senescence. Oncogene 32(22):2792-2798, 2013.

Zhang J, Espinoza LA, Kinders RJ, Lawrence SM, Pfister TD, Zhou M, Veenstra TD, Thorgeirsson SS, Jessup JM. NANOG modulates stemness in human colorectal cancer. Oncogene 32(37):4397-4405, 2013.

 

PNAS

Proceedings of the National Academy of Sciences

Alazawi W, Heath H, et al. Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis. Proc Natl Acad Sci U S A 110(21):8656-8661, 2013.

Arnold, ES, SC Ling, et al. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP- 43. Proc Natl Acad Sci U S A 110(8):E736- E745, 2013.

Burdick RC, Hu WS, Pathak VK. Nuclear import of APOBEC3F-labeled HIV-1 preintegration complexes. Proc Natl Acad Sci U S A 110(49):E4780-E4789, 2013.

Chen J, Feigenbaum L, et al. Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL-15R alpha. Proc Natl Acad Sci U S A 110(33):13534- 13539, 2013.

Feng MQ, Gao W, et al. Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma. Proc Natl Acad Sci U S A 110(12):E1083-E1091, 2013.

Kim TS, Park JE, Shukla A, Choi S, Murugan RN, Lee JH, Ahn M, Rhee K, Bang JK, Kim BY, Loncarek J, Erikson RL, Lee KS. Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152. Proc Natl Acad Sci U S A 110(50):E4849-E4857, 2013.

Kulkarni S, Qi Y, O’Huigin C, Pereyra F, Ramsuran V, McLaren P, Fellay J, Nelson G, Chen H, Liao W, Bass S, Apps R, Gao X, Yuki Y, Lied A, Ganesan A, Hunt PW, Deeks SG, Wolinsky S, Walker BD, Carrington M. Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease. Proc Natl Acad Sci U S A 2013. [Epub ahead of print. This article is not yet available in the print journal.]

Lin DC, Xu L, et al. Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers. Proc Natl Acad Sci U S A 110(15):6109-6114, 2013.

Patel, V, R Jalah, et al. DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge. Proc Natl Acad Sci U S A 110(8):2975-80, 2013.

Meyerson, JR, EEH Tran, et al. Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives. Proc Natl Acad Sci U S A 110(2):513-518, 2013.

Rein A. Murine leukemia virus p12 functions include hitchhiking into the nucleus. Proc Natl Acad Sci U S A 110(23):9195- 9196, 2013.

Song Y, Zhang Q, Kutlu B, Difilippantonio S, Bash R, Gilbert D, Yin C, O’Sullivan TN, Yang C, Kozlov S, Bullitt E, McCarthy KD, Kafri T, Louis DN, Miller CR, Hood L, Van Dyke T. Evolutionary etiology of high-grade astrocytomas. Proc Natl Acad Sci U S A 110(44):17933-17938, 2013.

Stavrou S, Nitta T, et al. Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex. Proc Natl Acad Sci U S A 110(22):9078- 9083, 2013.

Sundararaman SA, Liu WM, et al. Plasmodium falciparum-like parasites infecting wild apes in southern Cameroon do not represent a recurrent source of human malaria. Proc Natl Acad Sci U S A 110(17):7020-7025, 2013.

Takala-Harrison, S, TG Clark, et al. Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia. Proc Natl Acad Sci U S A 110(1):240-245, 2013.

Timofeeva, OA, NI Tarasova, et al. STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain. Proc Natl Acad Sci U S A 110(4):1267-1272, 2013.

Varadarajan J, McWilliams MJ, et al. Treatment with suboptimal doses of raltegravir leads to aberrant HIV-1 integrations. Proc Natl Acad Sci U S A 110(36):14747-14752, 2013.

 

Science

Science

Apps R, Carrington M. Response to comment on “Influence of HLA-C Expression Level on HIV Control.” Science 341(6151):1175, 2013.

Apps, R, Y Qi, et al. Influence of HLA-C expression level on HIV control. Science 340(6128):87-91, 2013.

Chaigne-Delalande B, Li FY, et al. Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D. Science 341(6142):186- 191, 2013.

Grohman JK, Gorelick RJ, et al. A guanosine-centric mechanism for RNA chaperone function. Science 340(6129):190- 195, 2013.

Hansen SG, Sacha JB, et al. Cytomegalovirus vectors violate CD8(+) T Cell epitope recognition paradigms. Science 340(6135):940-+, 2013.

Platinum highlightIida N, Dzutsev A, Stewart CA, Smith L, Bouladoux N, Weingarten RA, Molina DA, Salcedo R, Back T, Cramer S, Dai RM, Kiu H, Cardone M, Naik S, Patri AK, Wang E, Marincola FM, Frank KM, Belkaid Y, Trinchieri G, Goldszmid RS. Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment. Science 342(6161):967-970, 2013.

McLellan JS, Chen M, et al. Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science 340(6136):1113-1117, 2013.

McLellan JS, Chen M, Joyce MG, Sastry M, Stewart-Jones GBE, Yang YP, Zhang BS, Chen L, Srivatsan S, Zheng AQ, Zhou TQ, Graepel KW, Kumar A, Moin S, Boyington JC, Chuang GY, Soto C, Baxa U, Bakker AQ, Spits H, Beaumont T, Zheng ZZ, Xia NS, Ko SY, Todd JP, Rao S, Graham BS, Kwong PD. Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science 342(6158):592-598, 2013.

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