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Forum on the Microbiome and Autoimmunity
April 24, 2014
9AM - 4 PM
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Forum on the Microbiome and Autoimmunity

April 24, 2014 (9AM - 4 PM)
Natcher - Building 45
Rooms E1/E2
NIH-Bethesda

Please note that the registration for this conference has reached capacity.
Please contact Heather Leonard at heather.leonard2@nih.gov, to have your name added to a wait list.

The recent explosion in microbiome (commensal bacteria) research highlights the impact of host- microbiome interactions on maintenance of health and the development of disease. Current findings show that the microbiome is required for immune development and protective immune responses. It is also becoming clear that if there is a disruption or disorganization in the microbiome community inflammatory disease can occur. This is particularly evident with gastrointestinal autoimmune diseases such as inflammatory bowel disease. In this forum, we will focus on ongoing research into how the microbiome influences the development of autoimmune disease with particular emphasis on those conditions that have less well defined relationships with the microbiome. Our main goal is to foster discussion and collaboration in the larger field of research into microbiome-autoimmune disease interactions.

This meeting is sponsored by the NIH Microbiome Working Group, NCI, NIAID, NIAMS, NIH Office of Research in Women's Health and the Society for Women's Health Research.

Confirmed speakers:

Rachel Caspi (NEI): "TCR-specific activation of autoreactive T cells by endogenous microflora provokes spontaneous autoimunity in an immunologically privileged site"
http://www.nei.nih.gov/intramural/imm-reg.asp

Alessio Fasano (Harvard University School of Medicine): "Et tu Celiac? The Role of Microbes in Gluten Sensitive Enteropathy"
http://www.massgeneral.org/children/doctors/doctor.aspx?id=19184

Elizabeth Grice (Univ. of Pennsylvania School of Medicine): "Microbiome-host interactions in dysbiotic and inflammatory skin disease"
http://www.med.upenn.edu/gricelab/

Joseph Petrosino (Baylor College of Medicine): "Studies of the human microbiome and virome in type 1 diabetes"
https://www.bcm.edu/departments/molecular-virology-and-microbiology/?pmid=15214

Tim Hand (NIAID) "Gastrointestinal Infection Alters the Immune-Commensal Relationship"
http://www.niaid.nih.gov/LabsAndResources/labs/aboutlabs/lpd/mucosalimmunology/pages/belkaid.aspx

Jorge Henao-Mejia (Univ. of Pennsylvania School of Medicine) "Inflammasomes-mediated dysbiosis in health and disease"
http://www.henao-mejialab.com

Joseph Petrosino (Baylor College of Medicine): "Studies of the human microbiome and virome in type 1 diabetes"
https://www.bcm.edu/departments/molecular-virology-and-microbiology/?pmid=15214

Amy Proal (Autoimmunity Research Foundation) "Microbiome-induced Proteome dysbiosis in Autoimmune Disease"
http://mpkb.org/home/publications/proal_autoimmunity_2010

Brittany Chao (NIAID) "The role of the gut microbiome in Factor VIII inhibitor antibody formation: Novel target for inducing immune tolerance in Hemophilia A patients"
http://www.niaid.nih.gov/labsandresources/labs/aboutlabs/li/moleculardevelopmentimmunesystemsection
/Pages/lenardo.aspx

Jose Scher (New York University School of Medicine): "The Microbiome in Autoimmune Arthritis: A Century Later"
http://www.med.nyu.edu/biosketch/scherj01

Eric Triplett (University of Florida): "A tale of two studies: how cohort design can mask or reveal strong bacterial associations with type 1 diabetes autoimmunity".
http://microcell.ufl.edu/directory/faculty/eric-w-triplett/

General Information

For conference related questions please contact Howard Young
301.846.5743

Location


Natcher - Building 45
Rooms E1/E2
NIH-Bethesda

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