Chair: Eric Long
|9:15 - 10:00||
University of Massachusetts Medical School, Worcester, MA
Keynote Lecture: "NK cell control of T cell-regulated viral pathogenesis and persistence"
|10:00 - 10:30||
Mary Carrington, Laboratory of Experimental Immunology, NCI
"The influence of KIR variation in HIV disease"
|10:30 - 11:00||Break|
Chair: Dan McVicar
|11:00 - 11:30||
Bibiana Bielekova, Neuroimmunology Branch, NINDS
"Regulatory role of CD56bright NK cells in multiple sclerosis revealed by daclizumab therapy"
|11:30 - 11:45||
Konrad Krzewski, Laboratory of Immunogenetics, NIAID
"LAMP1: Not only a degranulation marker but an integral component of NK cell function"
|11:45 - 12:00||
Ainhoa Perez-Diez, Lab. of Cellular and Molecular Immunology, NIAID
"Resident peritoneal NK cells"
|12:00 - 12:15||
Diego A. Vargas-Inchaustegui, Vaccine Branch, CCR, NCI
"NK and CD4+ T cell co-operative immune responses correlate with control of disease in a macaque SIV infection model"
|12:15 - 12:30||
Bernard A.P. Lafont, Laboratory of Molecular Microbiology, NIAID
"Diversity of the Natural Killer cell Repertoire based on MHC class I recognition in macaques"
|12:30 - 1:30||Lunch|
Chair: Mary Carrington
|1:40 - 2:10||
Barbara Rehermann, Liver Diseases Branch, NIDDK
"Role of NK cells in Hepatitis C Virus Infection and Response to IFN-based Treatment"
|2:10 - 2:25||
Wolfgang Kastenmuller, Laboratory of Systems Biology, NIAID
"A spatially-organized multicellular innate immune response in the lymph node limits the systemic spread of tissue-invasive pathogens"
|2:25 - 2:40||
Romina Goldszmid, Laboratory of Experimental Immunology, NCI
"NK cell-derived IFN-γ orchestrates the cellular dynamics and differentiation of monocytes into interleukin-12 producing dendritic cells during the initiation of the Th1 response to Toxoplasma gondii infection"
|2:40 - 3:10||
Sumati Rajagopalan, Laboratory of Immunogenetics, NIAID
"Cellular senescence reprograms human natural killer cells to promote vascular remodeling"
|3:10 - 3:40||Break|
Chair: David Margulies
|3:40 - 4:10||
Andrew Brooks, Department of Microbiology and Immunology, University of Melbourne, Australia
"Recognition of HLA-A and HLA-B allotypes by KIR3DL1"
|4:10 - 4:25||
Geraldine O'Connor, Laboratory of Experimental Immunology, NCI
"Mutational Analysis Provides Insight into the Protective Role of KIR3DS1 in HIV Pathogenesis"
|4:25 - 4:40||
Feng-Yen Li, Laboratory of Immunology, NIAID
"XMEN disease is associated with loss of NKG2D expression and high susceptibility to lymphomas"
|4:40 - 4:55||
Xin Xu, Laboratory of Molecular Immunology, NIAID
"NK cells are required for optimal host defense, including the production of IL-22, against pulmonary K. pneumoniae infection in mice"
|4:55 - 5:10||
Wai Po Chong, Laboratory of Immunology, NEI
"Reciprocal interaction between NK cells and DCs regulates Th17 immune response by controlling the innate IFN-γ/IL-27 axis"
|5:15 - 5:30||NK Interest Group Discussion|