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Third Symposium on Translational Genomics
March 20-21, 2014
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Spacer Third Symposium on Translational Genomics - Agenda


Thursday, March 20, 2014

Welcome and Introductions
12:20 p.m. Snorri Thorgeirsson, Head, Center of Excellence in Integrative Cancer Biology and Genomics
Opening Address
12:30 p.m. Ed Liu, The Jackson Laboratory
"Combinatorics and Cancer Biology"
Keynote Address
1:00 p.m. Frank McCormick, University of California San Francisco
"New Approaches to Targeting RAS"
Session I: GWAS/eQTL: Translational Inferences
(chairs: Laufey Amundadottir and Perwez Hussain)
1:35 p.m Maria Teresa Landi, Division of Cancer Epidemiology & Genetics, NCI
"Characterizing the Genetic Basis of Methylome Diversity in Histologically Normal Human Lung Tissue"
2:10 p.m. Simon Gayther, University of Southern California
"Functional Characterization of Ovarian Cancer Susceptibility Loci Identified by Genome Wide Association Studies"
2:45 p.m. Break
3:05 p.m. Ludmila Prokunina-Olsson, Division of Cancer Epidemiology & Genetics, NCI
"From Genetics to Translational Genomics and Clinical Implementation of GWAS Findings"
3:35 p.m. Peggy Farnham, University of Southern California
"Using GWAS, Epigenomics, and Genome Engineering to Characterize Cancer-Associated Enhancers"
4:05 p.m. Poster Session

Friday, March 21, 2014

Keynote Address
8:30 a.m. George Church, Harvard University
"New Technologies for Disease Prevention"
Session II: Tumor Heterogeneity: Implications for Clinical Application
(chairs: Paul Meltzer and Thomas Ried)
9:05 a.m. Charles Swanton, University College London
"Tumour Heterogeneity and Cancer Evolution"
9:40 a.m. Sanford Markowitz, Case Western Reserve University
"Genetic Pathways in Colon Cancer"
10:15 a.m. Break
10:45 a.m. Thea Tlsty, University of California San Francisco
"Stochastic Cellular States Associated with Malignancy
11:20 a.m. Michael T. Barrett, Translational Genomics Research Institute
"Clonal Heterogeneity and Clinical Phenotypes"
11:55 a.m. Lunch
Session III: Genomic Oncology: State of the Art
(chairs: Javed Khan and Snorri Thorgeirsson)
1:00 p.m. Louis Staudt, Center for Cancer Research, NCI
"Using Genomics to Understand Response and Resistance to Targeted Therapy in Lymphoma"
1:35 p.m. Jean Claude Zenklusen, Center for Cancer Genomics, NCI
"The State of The Cancer Genome Atlas"
2:10 p.m. Stephen Baylin, Johns Hopkins University
"Epigenomics, The Cancer Epigenome and Translational Implications"
2:45 p.m. Break
Session IV: Metabolomics in Oncology: Therapeutic Potential
(chairs: Xin Wang and Tim Greten)
3:00 p.m. Xin Wang, Center for Cancer Research, NCI
"Integrative Genomics - Insights into Tumor Heterogeneity and Molecular Pathogenesis of Liver Cancer"
3:35 p.m. Marcin Kortylewski, City of Hope
"Immunostimulatory CpG-siRNAs: An Opportunity for Combinatorial Cancer Therapy"
4:10 p.m. Marston Linehan, Center for Cancer Research, NCI
"Targeting the Metabolic Basis of Kidney Cancer"
Closing Remarks
4:45 p.m. Thomas Ried, Co-chair, symposium planning committee
General Information

For conference related questions please contact Laura Hooper


Natcher Auditorium,
NIH Bethesda

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National Cancer Institute Human and Health Services National Institutes of Health