Laboratory Animal Sciences Program
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Quarantine and Rederivation Procedures


Rodents that are ordered from non-approved sources must be quarantined and special arrangements made with the LASP-Bethesda. This is generally done at the Receiving and Quarantine (R&Q) Facility located in Frederick, with the exception of mice destined for housing in the Building 10 ACRF animal facility. The length of the quarantine period is dependent on the source of the shipment and accompanying health report. Rodents from approved sources are delivered directly to DVR animal facilities and undergo quarantine and stabilization according to DVR standard operating procedures.This quarantine is required by NIH Manual Chapter 3043-1, Introduction of Rodents and Rodents Products and provides investigators with rodents of defined, specific pathogen-free (SPF) health status through the quarantine and testing of imported animals and the exclusion of animals harboring undesirable organisms.

Large Animals

Newly purchased dogs, cats, nonhuman primates, and livestock undergo prescribed procedures for quarantine in Division of Veterinary Resources (DVR) Quarantine Facilities in Poolesville before they are introduced into NIH animal colonies to assure that they are disease-free and in a condition that meets research criteria. Animals are then held in continued quarantine for monitoring to detect signs of illness or unsuitability, and for acclimation and stabilization into the laboratory environment. Investigators must have an approved Animal Study Proposal prior to quarantine.


R&Q imports rodents with undesirable pathogens and rederives them to SPF status, thus allowing investigators access to virtually any strain. This program is available to any investigator with a current Animal Study Proposal. The program utilizes embryo transfer to rederive strains coming from facilities with known health problems and for strains in Quarantine that test positive for an unexpected pathogen. Strains selected for inclusion into the NCI-Mouse Repository are also rederived before being distributed from the Animal Production Area.

General Information

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Scheduling Service

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R&Q Pricing

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DVR Pricing

Electronic Forms

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Submission of Mice for Rederivation to Specific Pathogen Free (SPF) Status

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Request for the Importation of Animals into NCI-Frederick Receiving and Quarantine Facility

Contact Information

Dr. Robert Hoyt

Animal Program Director - Bethesda

Phone: 301-435-5732


Dr. Wayne O’Brien

Facility Veterinarian


Phone: 301-402-0123

Fax: 301-402-0486


Dr. Joanne M. Smith

Facility Veterinarian

14F, 14G

Phone: 301-496-5257

Fax: 301-402-4258


Dr. Tanya Burkholder

Facility Veterinarian


Phone: 301-496-9201

Fax: 301-402-0377


Dr. Boris Skopets

Facility Veterinarian


Phone: 301-451-9476

Fax: 301-402-0378


Dr. Lyn Colenda

Facility Veterinarian

NIHAC 100 and 102

Phone: 301-402-5116

Fax: 301-496-0353

Dr. Richard Herbert

Facility Veterinarian


Phone: 301-827-4230 (office)and (301) 496-1535 (Vivarium)

Fax: 301-480-4116


Dr. Ashley Reynolds, D.V.M.

Facility Veterinarian

10/CRC and ACRF (Floors 12 and 13)

Phone: 301-496-1535

Fax: 301-402-1295


Dr. Rhonda Pung

Facility Veterinarian

41, 14DS

Phone: 301-496-5346

Fax: 301-496-1276



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