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Speed Congenics

Full-Genome Scan of an N4 Backcross Animal

Figure 2: Full-Genome Scan of an N4 Backcross Animal

Partial representation of a full-genome scan at backcross generation N4 (only 14 of 19 autosomes shown). Note that microsatellite markers flanking the gene of interest (Ifngr1, chromosome 10, 15 cM) are of recipient genetic background (green) indicating less than 16 cM of surrounding donor genome carry-over (approximately equivalent to a conventional N7 backcross). Chromosomes 4, 8, and 9 still contain significant amounts of donor strain DNA (red). Centimorgan positions of microsatellite markers are according to the Mouse Genome Database (MGD, The Jackson Laboratory).

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