Laboratory Animal Sciences Program
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Microtomy

Microtomy is Cutting Edge Work! It is the area of the laboratory, where blocks (usually in paraffin) are sectioned to produce slides that can be evaluated microscopically. A level of expertise rarely found anywhere else. These expertise include, but are not limited to:

  • Complex serial and step sectioning
    • On mice and other organisms
  • Cutting of plastic resins
  • Cutting of extremely thick or thin sections (2 µ to 1000 µ)
  • Routine Hematoxylin and Eosin slides (H & E’s): great quality slides are done in a timely manner

Our expert histologists are able to zero-in on small details and minute structures.

  • Also specializing in rodent embryos, can target specific locations following the M.H. Kaufmann’s "The Atlas of Mouse Developement"


Cryotomy – Frozen Sectioning

Frozen or fixed sections are used as an alternative to formalin fixed paraffin embedded (FFPE) tissues. Frozen sections are used when the normal fixation/processing regime may denature the target. Examples where this may be important are:

  • Demonstration of lipids
  • Enzyme histochemistry
  • Beta Galactosidase
  • Immunohistochemistry
  • Special stains

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