Available Strain Details

Strain Information
Common Strain Name: SV11 Pricing and Ordering Information
Strain Nomenclature: C57BL/6-Tg(TAg)11Bri/Nci
Animal State: Cryoarchived Strains
Release Category (Required for MTA form): B1,D


Strain Description: Mice develop choroid plexus carcinoma by 3.5 to 4 months of age. This phenotype is 100% penetrant.
Mutation Information
Mutation Type: Transgenic
Gene Name:
Gene Symbol:
Transgene Name: SV40 Large T antigen
Transgene Symbol: TAg
Promotor Name: Simian virus 40
Promotor Symbol: SV40
Current Genetic Background: C57BL/6J
Approx. Generation: 16
Organ Site: Brain
Additional Information
Cryopreservation Mating Scheme: The cryopreservation mating scheme is C57BL/6 females x hemizygous males. When maintained as a live colony, breeder pairs were distributed as a hemizygote (male or female) x wildtype C57BL/6 (male or female).
Genotyping Information: Protocol 1: Allele: Tg(TAg)11Bri
Donating Investigator: Dr. Terry Van Dyke

Key Reference: Chen JD, Van Dyke T. 1991. Uniform cell-autonomous tumorigenesis of the choroid plexus by papovavirus large T antigens. Mol Cell Biol. 11:5968-76. PMID: 1658622 [Pubmed Abstract]