Available Strain Details

Strain Information
Common Strain Name: WAP-rtTA-Cre Pricing and Ordering Information
Strain Nomenclature: C57BL/6-Tg(Wap-rtTA-cre)10Whl/Nci
Animal State: Cryoarchived Strains
Release Category (Required for MTA form): C1,D


Strain Description: Cre recombinase expression is localized to the mammary gland, which is controlled by administration of doxycycline. The strain is used to induce Cre-mediated DNA recombination in the mammary gland.
Mutation Information
Mutation Type: Transgenic
Gene Name:
Gene Symbol:
Transgene Name: Cre recombinase
Transgene Symbol: Cre
Promotor Name: Whey acidic protein (mouse)
Promotor Symbol: WAP
Current Genetic Background: C57BL/6
Approx. Generation: 14
Organ Site: Breast
Additional Information
Cryopreservation Mating Scheme: The cryopreservation mating scheme is C57BL/6 females x hemizygous males. When maintained as a live colony, breeder pairs were distributed as a hemizygote (male or female) x wildtype C57BL/6 (male or female).
Genotyping Information: Protocol 1: Allele: Tg(Wap-rtTA-cre)10Whl
Protocol 2: Allele: Tg(Wap-rtTA-cre)10Whl
Donating Investigator: Dr. Wen-Hwa Lee

Key Reference: Utomo ARH, Kikitin AY, Lee WH. 1999. Temporal, spatial, and cell type-specific control of Cre-mediated DNA recombination in transgenic mice. Nature Biotechnology 17:1091-96. PMID: 10545915 [Pubmed Abstract]