Available Strain Details

Strain Information
Common Strain Name: HB-PLAP Pricing and Ordering Information
Strain Nomenclature: FVB-Tg(ACTB-ALPP)01Jrst/Nci
Animal State: Cryoarchived Strains
Release Category (Required for MTA form): C1


Strain Description: Transgenic mice exhibit a heat-stable alkaline phosphatase activity (human ALPP) in all tissues.
Mutation Information
Mutation Type: Transgenic
Gene Name:
Gene Symbol:
Transgene Name: human placental alkaline phosphatase
Transgene Symbol: PLAP
Promotor Name: human beta actin
Promotor Symbol: ACTB
Current Genetic Background: FVB/N
Approx. Generation: 3
Organ Site:
Additional Information
Cryopreservation Mating Scheme: The cryopreservation mating scheme is FVB females x hemizygous males. When maintained as a live colony, breeder pairs were distributed as a hemizygote (male or female) x wildtype FVB (male or female).
Genotyping Information: Protocol 1: Allele: Tg(ACTB-ALPP)01Jrst
Protocol 2: Allele: Tg(ACTB-ALPP)01Jrst
Donating Investigator: Dr. James Stringer

Key Reference: DePrimo SE, Stambrook PJ, Stringer JR. 1996 Human placental alkaline phosphatase as a histochemical marker of gene expression in transgenic mice. Transgenic Res. 6:459-466. PMID: 8840529 [Pubmed Abstract]