Selective Bibliography of Dr. Hendrik Luesch
Debbie and Sylvia DeSantis Chair in Natural Products Drug Discovery and Development
Professor and Chair of the Department of Medicinal Chemistry
University of Florida

“Natural Products from Marine Cyanobacteria as Starting Points for Drug Discovery and Development”
Thursday, May 30, 2019

1.  Cai W, Ratnayake R, Gerber MH, Chen QY, Yu Y, Derendorf H, Trevino JG, Luesch H
Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model
Investigational New Drugs 37 (2):364-374 Apr 2019

2.  Liang X, Luo D, Yan JL, Rezaei MA, Salvador-Reyes LA, Gunasekera SP, Li C, Ye T, Paul VJ, Luesch H
Discovery of Amantamide, a Selective CXCR7 Agonist from Marine Cyanobacteria
Organic Letters 21 (6):1622-1626 Mar 15 2019

3.  Luo D, Putra MY, Ye T, Paul VJ, Luesch H
Isolation, Structure Elucidation and Biological Evaluation of Lagunamide D: A New Cytotoxic Macrocyclic Depsipeptide from Marine Cyanobacteria
Marine Drugs 17 (2):Feb 1 2019

4.  Gunasekera SP, Meyer JL, Ding Y, Abboud KA, Luo D, Campbell JE, Angerhofer A, Goodsell JL, Raymundo LJ, Liu J, Ye T, Luesch H, Teplitski M, Paul VJ
Chemical and Metagenomic Studies of the Lethal Black Band Disease of Corals Reveal Two Broadly Distributed, Redox-Sensitive Mixed Polyketide/Peptide Macrocycles
Journal of Natural Products 82 (1):111-121 Jan 25 2019

5.  Brumley D, Spencer KA, Gunasekera SP, Sauvage T, Biggs J, Paul VJ, Luesch H
Isolation and Characterization of Anaephenes A-C, Alkylphenols from a Filamentous Cyanobacterium ( Hormoscilla sp., Oscillatoriales)
Journal of Natural Products 81 (12):2716-2721 Dec 28 2018

6.  Jonus HC, Hanberry BS, Khatu S, Kim J, Luesch H, Dang LH, Bartlett MG, Zastre JA
The adaptive regulation of thiamine pyrophosphokinase-1 facilitates malignant growth during supplemental thiamine conditions
Oncotarget 9 (83):35422-35438 Oct 23 2018

7.  Yan JL, Cheng Y, Chen J, Ratnayake R, Dang LH, Luesch H, Guo Y, Ye T
Total Synthesis of Asperphenins A and B
Organic Letters 20 (19):6170-6173 Oct 5 2018

8.  Al-Awadhi FH, Gao B, Rezaei MA, Kwan JC, Li C, Ye T, Paul VJ, Luesch H
Discovery, Synthesis, Pharmacological Profiling, and Biological Characterization of Brintonamides A-E, Novel Dual Protease and GPCR Modulators from a Marine Cyanobacterium
Journal of Medicinal Chemistry 61 (14):6364-6378 Jul 26 2018

9.  Cai W, Matthew S, Chen QY, Paul VJ, Luesch H
Discovery of new A- and B-type laxaphycins with synergistic anticancer activity
Bioorganic and Medicinal Chemistry 26 (9):2310-2319 May 15 2018

10.  Garrison AT, Abouelhassan Y, Kallifidas D, Tan H, Kim YS, Jin S, Luesch H, Huigens RW, 3rd
An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration
Journal of Medicinal Chemistry 61 (9):3962-3983 May 10 2018

Updated 05/23/19