Platinum Publications, July 31–September 30, 2015

Ashley DeVine
Platinum Publications graphic

Platinum Publications are selected from articles by NCI at Frederick scientists published in 42 prestigious science journals. This list represents articles published during the time period shown above, as generated from PubMed.

Articles designated as Platinum Highlights are noteworthy articles selected by Dr. Craig Reynolds, associate director, National Cancer Institute, from among the most recently published Platinum Publications.

The Scientific Library maintains the NCI at Frederick-in-Print database, a collection of citations for journal articles authored by NCI at Frederick employees since 1997. 

Platinum highlight

denotes Platinum Highlight article. Click on the image to go to the Platinum Highlight article. 





Guven-Maiorov E, Keskin O, Gursoy A, Nussinov R. A structural view of negative regulation of the toll-like receptor-mediated inflammatory pathway. Biophys J 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Muratcioglu S, Presman DM, Pooley JR, Grontved L, Hager GL, Nussinov R, Keskin O, Gursoy A. Structural modeling of GR interactions with the SWI/SNF chromatin remodeling complex and C/EBP. Biophys J 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Nussinov R, Tsai CJ. The role of allostery in the termination of second messenger signaling. Biophys J 2015.
[Epub ahead of print - This article is not yet available in the print journal.]






Parsons J, Munro S, Pine PS, McDaniel J, Mehaffey M, Salit M. Using mixtures of biological samples as process controls for RNA-sequencing experiments. BMC Genomics 16(1):708, 2015.



Ridnour LA, Cheng RYS, Weiss JM, Kaur S, Soto-Pantoja DR, Basudhar D, Heinecke JL, Stewart CA, DeGraff W, Sowers AL, Thetford A, Kesarwala AH, Roberts DD, Young HA, Mitchell JB, Trinchieri G, Wiltrout RH, Wink DA. NOS inhibition modulates immune polarization and improves radiation-induced tumor growth delay. Cancer Res 75(14):2788–2799, 2015.






Pan P, Skaer CW, Wang HT, Stirdivant SM, Young MR, Oshima K, Stoner GD, Lechner JF, Huang YW, Wang LS. Black raspberries suppress colonic adenoma development in ApcMin/+ mice: relation to metabolite profiles. Carcinogenesis 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Seow WJ, Zhang LP, Vermeulen R, Tang XJ, Hu W, Bassig BA, Ji ZY, Shiels MS, Kemp TJ, Shen M, Qiu CY, Reiss B, Freeman LEB, Blair A, Kim C, Guo WH, Wen CJ, Li LY, Pinto LA, Huang HL, Smith MT, Hildesheim A, Rothman N, Lan Q. Circulating immune/inflammation markers in Chinese workers occupationally exposed to formaldehyde. Carcinogenesis 36(8):852–857, 2015.






Kanekiyo M, Bu W, Joyce MG, Meng G, Whittle JR, Baxa U, Yamamoto T, Narpala S, Todd JP, Rao SS, McDermott AB, Koup RA, Rossmann MG, Mascola JR, Graham BS, Cohen JI, Nabel GJ. Rational design of an Epstein-Barr virus vaccine targeting the receptor-binding site. Cell 162(5):1090–1100, 2015.






Sharma BK, Kolhe R, Black SM, Keller JR, Mivechi NF, Satyanarayana A. Inhibitor of differentiation 1 transcription factor promotes metabolic reprogramming in hepatocellular carcinoma cells. FASEB J 2015.
[Epub ahead of print - This article is not yet available in the print journal.]






Lawrence MG, Leiding JW, Lyons JJ, Hsu AP, Nelson CC, Jones N, Fitzgerald A, Chien WW, Workman L, Platts-Mills TA, Brewer C, Gafni RI, Stone KD, Milner JD, Holland SM. GATA3 haploinsufficiency does not block allergic sensitization or atopic disease. J Allergy Clin Immunol 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Odio CD, Lee Milligan K, McGowan K, Rudman Spergel AK, Bishop R, Boris L, Urban A, Welch P, Heller T, Kleiner D, Jackson MA, Holland SM, Freeman AF. Endemic mycoses in patients with STAT3-mutated hyper-IgE (Job) syndrome. J Allergy Clin Immunol 2015.
[Epub ahead of print - This article is not yet available in the print journal.]






Fulgenzi G, Tomassoni-Ardori F, Babini L, Becker J, Barrick C, Puverel S, Tessarollo L. BDNF modulates heart contraction force and long-term homeostasis through truncated TrkB.T1 receptor activation. J Cell Biol 2015.
[Epub ahead of print - This article is not yet available in the print journal.]






Giacomin PR, Moy RH, Noti M, Osborne LC, Siracusa MC, Alenghat T, Liu B, McCorkell KA, Troy AE, Rak GD, Hu Y, May MJ, Ma HL, Fouser LA, Sonnenberg GF, Artis D. Epithelial-intrinsic IKKalpha expression regulates group 3 innate lymphoid cell responses and antibacterial immunity. J Exp Med 212(10):1513–1528, 2015.






Alhajjat AM, Strong BS, Lee AE, Turner LE, Wadhwani RK, Ortaldo JR, Heusel JW, Shaaban AF. Prenatal allospecific NK cell tolerance hinges on instructive allorecognition through the activating receptor during development. J Immunol 195(4):1506–1516, 2015.

Ames E, Canter RJ, Grossenbacher SK, Mac S, Chen M, Smith RC, Hagino T, Perez-Cunningham J, Sckisel GD, Urayama S, Monjazeb AM, Fragoso RC, Sayers TJ, Murphy WJ. NK cells preferentially target tumor cells with a cancer Stem cell phenotype. J Immunol 195(8):4010–4019, 2015.

Zhu Z, Cuss SM, Singh V, Gurusamy D, Shoe JL, Leighty R, Bronte V, Hurwitz AA. CD4+ T cell help selectively enhances high-avidity tumor antigen-specific CD8+ T cells. J Immunol 2015.
[Epub ahead of print - This article is not yet available in the print journal.]






Evans TI, Li H, Schafer JL, Klatt NR, Hao XP, Traslavina RP, Estes JD, Brenchley JM, Reeves RK. SIV-induced translocation of bacterial products in the liver mobilizes myeloid dendritic and natural killer cells associated with liver damage. J Infect Dis 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Goedert JJ, Martin MP, Vitale F, Lauria C, Whitby D, Qi Y, Gao X, Carrington M. Risk of classic Kaposi sarcoma with combinations of killer immunoglobulin-like receptor and human leukocyte antigen loci: a population-based case-control study. J Infect Dis 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

von Stockenstrom S, Odevall L, Lee E, Sinclair E, Bacchetti P, Killian M, Epling L, Shao W, Hoh R, Ho T, Faria NR, Lemey P, Albert J, Hunt P, Loeb L, Pilcher C, Poole L, Hatano H, Somsouk M, Douek D, Boritz E, Deeks SG, Hecht FM, Palmer S. Longitudinal genetic characterization reveals that cell proliferation maintains a persistent HIV type 1 DNA pool during effective HIV therapy. J Infect Dis 212(4):596–607, 2015.






Garcia-Vallve S, Guasch L, Tomas-Hernandez S, del Bas JM, Ollendorff V, Arola L, Pujadas G, Mulero M. Peroxisome proliferator-activated receptor gamma (PPAR gamma) and ligand choreography: newcomers take the stage. J Med Chem 58(14):5381–5394, 2015.

La Regina G, Bai RL, Coluccia A, Farniglini V, Pelliccia S, Passacantilli S, Mazzoccoli C, Ruggieri V, Verrico A, Miele A, Monti L, Nalli M, Alfonsi R, Di Marcotullio L, Gulino A, Ricci B, Soriani A, Santoni A, Caraglia M, Porto S, Da Pozzo E, Martini C, Brancale A, Marinelli L, Novellino E, Vultaggio S, Varasi M, Mercurio C, Bigogno C, Dondio G, Hamel E, Lavia P, Silvestri R. New Indole tubulin assembly inhibitors cause stable arrest of mitotic progression, enhanced stimulation of natural killer cell cytotoxic activity, and repression of hedgehog-dependent cancer. J Med Chem 58(15):5789–5807, 2015.





JOURNAL OF THE NATIONAL CANCER INSTITUTE                                   

Figueroa JD, Koutros S, Colt JS, Kogevinas M, Garcia-Closas M, Real FX, Friesen MC, Baris D, Stewart P, Schwenn M, Johnson A, Karagas MR, Armenti KR, Moore LE, Schned A, Lenz P, Prokunina-Olsson L, Banday AR, Paquin A, Ylaya K, Chung JY, Hewitt SM, Nickerson ML, Tardon A, Serra C, Carrato A, Garcia-Closas R, Lloreta J, Malats N, Fraumeni JF, Jr., Chanock SJ, Chatterjee N, Rothman N, Silverman DT. Modification of occupational exposures on bladder cancer risk by common genetic polymorphisms. J Natl Cancer Inst 107(11):2015.

Goedert JJ, Jones G, Hua X, Xu X, Yu G, Flores R, Falk RT, Gail MH, Shi J, Ravel J, Feigelson HS. Investigation of the association between the fecal microbiota and breast cancer in postmenopausal women: a population-based case-control pilot study. J Natl Cancer Inst 107(8):2015.

Shiels MS, Katki HA, Hildesheim A, Pfeiffer RM, Engels EA, Williams M, Kemp TJ, Caporaso NE, Pinto LA, Chaturvedi AK. Circulating inflammation markers, risk of lung cancer, and utility for risk stratification. J Natl Cancer Inst 107(10):2015.






Breed MW, Elser SE, Torben W, Jordan AP, Aye PP, Midkiff C, Schiro F, Sugimoto C, Alvarez-Hernandez X, Blair RV, Somasunderam A, Utay NS, Kuroda MJ, Pahar B, Wiseman RW, O'Connor DH, LaBranche CC, Montefiori DC, Marsh M, Li Y, Piatak M, Jr., Lifson JD, Keele BF, Fultz PN, Lackner AA, Hoxie JA. Elite control, gut CD4 T cell sparing, and enhanced mucosal T cell responses in Macaca nemestrina infected by an SIV lacking a gp41 trafficking motif. J Virol 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Chowdhury A, Hayes TL, Bosinger SE, Lawson BO, Vanderford T, Schmitz JE, Paiardini M, Betts M, Chahroudi A, Estes JD, Silvestri G. Differential impact of in vivo CD8(+) T lymphocyte depletion in controller versus progressor simian immunodeficiency virus-infected macaques. J Virol 89(17):8677–8686, 2015.

Dick RA, Datta SA, Nanda H, Fang X, Wen Y, Barros M, Wang YX, Rein A, Vogt VM. Hydrodynamic and membrane binding properties of purified Rous sarcoma virus Gag protein. J Virol 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Fontana J, Jurado KA, Cheng NQ, Ly NL, Fuchs JR, Gorelick RJ, Engelman AN, Steven AC. Distribution and Redistribution of HIV-1 Nucleocapsid protein in immature, mature, and integrase-inhibited virions: a role for integrase in maturation. J Virol 89(19):9765–9780, 2015.

Martins MA, Tully DC, Cruz MA, Power KA, Veloso de Santana MG, Bean DJ, Ogilvie CB, Gadgil R, Lima NS, Magnani DM, Ejima K, Allison DB, Piatak M, Jr., Altman JD, Parks CL, Rakasz EG, Capuano S, 3rd, Galler R, Bonaldo MC, Lifson JD, Allen TM, Watkins DI. Vaccine-induced SIV-specific CD8+ T-cell responses focused on a single Nef epitope select for escape variants shortly after infection. J Virol 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Olesen R, Vigano S, Rasmussen T, Sogaard OS, Ouyang Z, Buzon M, Bashirova A, Carrington M, Palmer S, Brinkmann CR, Yu XG, Ostergaard L, Tolstrup M, Lichterfeld M. Innate immune activity correlates with CD4 T cell-associated HIV-1 DNA decline during latency-reversing treatment with panobinostat. J Virol 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Sardo L, Hatch SC, Chen J, Nikolaitchik O, Burdick RC, Chen, Westlake CJ, Lockett S, Pathak VK, Hu WS. The dynamics of HIV-1 RNA near the plasma membrane during virus assembly. J Virol 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Shen XY, Duffy R, Howington R, Cope A, Sadagopal S, Park H, Pal R, Kwa S, Ding S, Yang OO, Fouda GG, Le Grand R, Bolton D, Esteban M, Phogat S, Roederer M, Amara RR, Picker LJ, Seder RA, McElrath MJ, Barnett S, Permar SR, Shattock R, DeVico AL, Felber BK, Pavlakis GN, Pantaleo G, Korber BT, Montefiori DC, Tomaras GD. Vaccine-induced linear epitope-specific antibodies to simian immunodeficiency virus SIVmac239 envelope are distinct from those induced to the human immunodeficiency virus type 1 envelope in nonhuman primates. J Virol 89(16):8643–8650, 2015.

Shunaeva A, Potashnikova D, Pichugin A, Mishina A, Filatov A, Nikolaitchik O, Hu WS, Mazurov D. Improvement of HIV-1 and HTLV-1 replication-dependent vectors via optimization of reporter gene reconstitution and modification with intronic shRNA. J Virol 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Tekeste SS, Wilkinson TA, Weiner EM, Xu X, Miller JT, Le Grice SF, Clubb RT, Chow SA. Interaction between reverse transcriptase and integrase is required for reverse transcription during HIV-1 replication. J Virol 2015.
[Epub ahead of print - This article is not yet available in the print journal.]






Wilson WH, Young RM, Schmitz R, Yang YD, Pittaluga S, Wright G, Lih CJ, Williams PM, Shaffer AL, Gerecitano J, de Vos S, Goy A, Kenkre VP, Barr PM, Blum KA, Shustov A, Advani R, Fowler NH, Vose JM, Elstrom RL, Habermann TM, Barrientos JC, McGreivy J, Fardis M, Chang BY, Clow F, Munneke B, Moussa D, Beaupre DM, Staudt LM. Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma. Nat Med 21(8):922–926, 2015.



Petersdorf EW, Malkki M, O'HUigin C, Carrington M, Gooley T, Haagenson MD, Horowitz MM, Spellman SR, Wang T, Stevenson P. High HLA-DP expression and graft-versus-host disease. N Engl J Med 373(7):599–609, 2015.






Levay A, Brenneman R, Hoinka J, Sant D, Cardone M, Trinchieri G, Przytycka TM, Berezhnoy A. Identifying high-affinity aptamer ligands with defined cross-reactivity using high-throughput guided systematic evolution of ligands by exponential enrichment. Nucleic Acids Res 43(12):2015.






Xing R, Li L, Chen L, Gao Z, Wang H, Li W, Cui J, Tian G, Liang Q, Yu J, Sung JJ, Luo G, Gao H, Xu X, Yang H, Wang J, Zhang X, Wang JM, Huang J, Yu Y, Wang J, Lu Y. Copy number variations of HLA-I and activation of NKp30 pathway determine the sensitivity of gastric cancer cells to the cytotoxicity of natural killer cells. Oncogene 2015.
[Epub ahead of print - This article is not yet available in the print journal.]






Clausen R, Ma B, Nussinov R, Shehu A. Mapping the conformation space of wildtype and mutant H-Ras with a memetic, cellular, and multiscale evolutionary algorithm. PLoS Comput Biol 11(9):e1004470, 2015.






Iyengar SK, Sedor JR, Freedman BI, Kao WH, Kretzler M, Keller BJ, Abboud HE, Adler SG, Best LG, Bowden DW, Burlock A, Chen YD, Cole SA, Comeau ME, Curtis JM, Divers J, Drechsler C, Duggirala R, Elston RC, Guo X, Huang H, Hoffmann MM, Howard BV, Ipp E, Kimmel PL, Klag MJ, Knowler WC, Kohn OF, Leak TS, Leehey DJ, Li M, Malhotra A, Marz W, Nair V, Nelson RG, Nicholas SB, O'Brien SJ, Pahl MV, Parekh RS, Pezzolesi MG, Rasooly RS, Rotimi CN, Rotter JI, Schelling JR, Seldin MF, Shah VO, Smiles AM, Smith MW, Taylor KD, Thameem F, Thornley-Brown DP, Truitt BJ, Wanner C, Weil EJ, Winkler CA, Zager PG, Igo RP, Jr., Hanson RL, Langefeld CD. Genome-wide association and trans-ethnic meta-analysis for advanced diabetic kidney disease: family investigation of nephropathy and diabetes (FIND). PLoS Genet 11(8):e1005352, 2015.






Carrick DM, Mehaffey MG, Sachs MC, Altekruse S, Camalier C, Chuaqui R, Cozen W, Das B, Hernandez BY, Lih CJ, Lynch CF, Makhlouf H, McGregor P, McShane LM, Rohan JP, Walsh WD, Williams PM, Gillanders EM, Mechanic LE, Schully SD. Robustness of next generation sequencing on older formalin-fixed paraffin-embedded tissue. PLoS One 10(7):e0127353, 2015.

Chatterjee A, Ratner DM, Ryan CM, Johnson PJ, O’Keefe BR, Secor WE, Anderson DJ, Robbins PW, Samuelson J. Anti-retroviral lectins have modest effects on adherence of Trichomonas vaginalis to epithelial cells in vitro and on recovery of tritrichomonas foetus in a mouse vaginal model. PLoS One 10(8):e0135340, 2015.

Cunningham TJ, Brade T, Sandell LL, Lewandoski M, Trainor PA, Colas A, Mercola M, Duester G. Retinoic acid activity in undifferentiated neural progenitors is sufficient to fulfill its role in restricting fgf8 expression for somitogenesis. PLoS One 10(9):e0137894, 2015.

Grossman Z, Avidor B, Mor Z, Chowers M, Levy I, Shahar E, Riesenberg K, Sthoeger Z, Maayan S, Shao W, Lorber M, Olstein-Pops K, Elbirt D, Elinav H, Asher I, Averbuch D, Istomin V, Gottesman BS, Kedem E, Girshengorn S, Kra-Oz Z, Shemer Avni Y, Radian Sade S, Turner D, Maldarelli F. A population-structured HIV epidemic in Israel: roles of risk and ethnicity. PLoS One 10(8):e0135061, 2015.

Matsui K, Adelsberger JW, Kemp TJ, Baseler MW, Ledgerwood JE, Pinto LA. Circulating CXCR5+CD4+ T Follicular-like helper cell and memory B cell responses to human papillomavirus vaccines. PLoS One 10(9):e0137195, 2015.

Pluchino KM, Esposito D, Moen JK, Hall MD, Madigan JP, Shukla S, Procter LV, Wall VE, Schneider TD, Pringle I, Ambudkar SV, Gill DR, Hyde SC, Gottesman MM. Identification of a cryptic bacterial promoter in mouse (mdr1a) P-glycoprotein cDNA. PLoS One 10(8):e0136396, 2015.

Zhao BM, Keasey SL, Tropea JE, Lountos GT, Dyas BK, Cherry S, Raran-Kurussi S, Waugh DS, Ulrich RG. Phosphotyrosine substrate sequence motifs for dual specificity phosphatases. PLoS One 10(8):e0134984, 2015.






Fuchs SP, Martinez-Navio JM, Piatak M, Jr., Lifson JD, Gao G, Desrosiers RC. AAV-delivered antibody mediates significant protective effects against SIVmac239 challenge in the absence of neutralizing activity. PLoS Pathog 11(8):e1005090, 2015.






Cortese-Krott MM, Kuhnle GG, Dyson A, Fernandez BO, Grman M, DuMond JF, Barrow MP, McLeod G, Nakagawa H, Ondrias K, Nagy P, King SB, Saavedra JE, Keefer LK, Singer M, Kelm M, Butler AR, Feelisch M. Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl. Proc Natl Acad Sci U S A 112(34):E4651–E4660, 2015.

Dimitrov DS, Jiang S, Ying T, Tseng CK, Zhang L, Yuen KY. No evidence for a superior platform to develop therapeutic antibodies rapidly in response to MERS-CoV and other emerging viruses. Proc Natl Acad Sci U S A 2015.
[Epub ahead of print - This article is not yet available in the print journal.]

Nagy-Smith K, Moore E, Schneider J, Tycko R. Molecular structure of monomorphic peptide fibrils within a kinetically trapped hydrogel network. Proc Natl Acad Sci U S A 112(32):9816–9821, 2015.

Zhang M, Mathews Griner LA, Ju W, Duveau DY, Guha R, Petrus MN, Wen B, Maeda M, Shinn P, Ferrer M, Conlon KD, Bamford RN, O'Shea JJ, Thomas CJ, Waldmann TA. Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia. Proc Natl Acad Sci U S A 2015.
[Epub ahead of print - This article is not yet available in the print journal.]






Barouch DH, Alter G, Broge T, Linde C, Ackerman ME, Brown EP, Borducchi EN, Smith KM, Nkolola JP, Liu JY, Shields J, Parenteau L, Whitney JB, Abbink P, Ng'ang'a DM, Seaman MS, Lavine CL, Perry JR, Li WJ, Colantonio AD, Lewis MG, Chen B, Wenschuh H, Reimer U, Piatak M, Lifson JD, Handley SA, Virgin HW, Koutsoukos M, Lorin C, Voss G, Weijtens M, Pau MG, Schuitemaker H. Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys. Science 349(6245):320–324, 2015.

Sudmant PH, Mallick S, Nelson BJ, Hormozdiari F, Krumm N, Huddleston J, Coe BP, Baker C, Nordenfelt S, Bamshad M, Jorde LB, Posukh OL, Sahakyan H, Watkins WS, Yepiskoposyan L, Abdullah MS, Bravi CM, Capelli C, Hervig T, Wee JT, Tyler-Smith C, van Driem G, Romero IG, Jha AR, Karachanak-Yankova S, Toncheva D, Comas D, Henn B, Kivisild T, Ruiz-Linares A, Sajantila A, Metspalu E, Parik J, Villems R, Starikovskaya EB, Ayodo G, Beall CM, Di Rienzo A, Hammer M, Khusainova R, Khusnutdinova E, Klitz W, Winkler C, Labuda D, Metspalu M, Tishkoff SA, Dryomov S, Sukernik R, Patterson N, Reich D, Eichler EE. Global diversity, population stratification, and selection of human copy number variation. Science 2015.
[Epub ahead of print - This article is not yet available in the print journal.]