Platinum Publications, July 1–July 28, 2016

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Platinum Publications are selected from articles by NCI at Frederick scientists published in 42 prestigious science journals. This list represents articles published during the time period shown above, as generated from PubMed.

Articles designated as Platinum Highlights are noteworthy articles selected by Dr. Craig Reynolds, associate director, National Cancer Institute, from among the most recently published Platinum Publications.

The Scientific Library maintains the NCI at Frederick Scientific Publications database, a collection of citations for journal articles authored by NCI at Frederick employees since 1997. 

Platinum highlight- Denotes Platinum Highlight article. Click on the image to go to the Platinum Highlight article.


JOURNAL OF BIOLOGICAL CHEMISTRY

Holdfeldt A, Skovbakke SL, Winther M, Gabl M, Nielsen C, Perez-Gassol I, Larsen CJ, Wang JM, Karlsson A, Dahlgren C, Forsman H, Franzyk H. The lipidated peptidomimetic Lau-[(S)-Aoc]-(Lys-betaNphe)6-NH2 is a novel formyl peptide receptor 2 agonist that activates both human and mouse neutrophil NADPH-oxidase. J Biol Chem 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

JOURNAL OF CLINICAL INVESTIGATION

Younes SA, Freeman ML, Mudd JC, Shive CL, Reynaldi A, Panigrahi S, Estes JD, Deleage C, Lucero C, Anderson J, Schacker TW, Davenport MP, McCune JM, Hunt PW, Lee SA, Serrano-Villar S, Debernardo RL, Jacobson JM, Canaday DH, Sekaly RP, Rodriguez B, Sieg SF, Lederman MM. IL-15 promotes activation and expansion of CD8(+) T cells in HIV-1 infection. J Clin Invest 126(7):2745-2756, 2016.

JOURNAL OF IMMUNOLOGY 

DeGottardi MQ, Okoye AA, Vaidya M, Talla A, Konfe AL, Reyes MD, Clock JA, Duell DM, Legasse AW, Sabnis A, Park BS, Axthelm MK, Estes JD, Reiman KA, Sekaly RP, Picker LJ. Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques. J Immunol 197(4):1183-98, 2016.

JOURNAL OF MEDICINAL CHEMISTRY 

Devambatla RKV, Namjoshi OA, Choudhary S, Hamel E, Shaffer CV, Rohena CC, Mooberry SL, Gangjee A. Design, Synthesis, and Preclinical Evaluation of 4-Substituted-5-methyl-furo 2,3-d pyrimidines as Microtubule Targeting Agents That Are Effective against Multidrug Resistant Cancer Cells. J Med Chem 59(12):5752-5765, 2016.

JOURNAL OF VIROLOGY 

Gach JS, Venzon D, Vaccari M, Keele BF, Franchini G, Forthal DN. The relationship between vaccine-induced antibody capture of infectious virus and infection outcomes following low-dose, repeated rectal challenge with SIVmac251. J Virol 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

Lopker MJ, Del Prete GQ, Estes JD, Li H, Reid C, Newman L, Lipkey L, Camus C, Easlick JL, Wang S, Decker JM, Bar KJ, Learn G, Pal R, Weiss DE, Hahn BH, Lifson JD, Shaw GM, Keele BF. Derivation and characterization of pathogenic transmitted/founder molecular clones from SIVsmE660 and SIVmac251 following mucosal infection. J Virol 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

NATURE 

Chaudhuri AR, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, de Ruiter JR, Daniel JA, Konstantinopoulos PA, Cortez D, Cantor SB, Fernandez-Capetillo O, Ge K, Jonkers J, Rottenberg S, Sharan SK, Nussenzweig A. Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature 535(7612):382-7, 2016.

NATURE MEDICINE 

Deeks SG, Lewin SR, Ross AL, Ananworanich J, Benkirane M, Cannon P, Chomont N, Douek D, Lifson JD, Lo YR, Kuritzkes D, Margolis D, Mellors J, Persaud D, Tucker JD, Barre-Sinoussi F, Alter G, Auerbach J, Autran B, Barouch DH, Behrens G, Cavazzana M, Chen Z, Cohen EA, Corbelli GM, Eholie S, Eyal N, Fidler S, Garcia L, Grossman C, Henderson G, Henrich TJ, Jefferys R, Kiem HP, McCune J, Moodley K, Newman PA, Nijhuis M, Nsubuga MS, Ott M, Palmer S, Richman D, Saez-Cirion A, Sharp M, Siliciano J, Silvestri G, Singh J, Spire B, Taylor J, Tolstrup M, Valente S, van Lunzen J, Walensky R, Wilson I, Zack J. International AIDS Society global scientific strategy: towards an HIV cure 2016. Nat Med 22(8):839-50, 2016.

NUCLEIC ACIDS RESEARCH

Desimmie BA, Burdick RC, Izumi T, Doi H, Shao W, Alvord WG, Sato K, Koyanagi Y, Jones S, Wilson E, Hill S, Maldarelli F, Hu WS, Pathak VK. APOBEC3 proteins can copackage and comutate HIV-1 genomes. Nucleic Acids Res 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

Metifiot M, Johnson BC, Kiselev E, Marler L, Zhao XZ, Burke TR, Jr., Marchand C, Hughes SH, Pommier Y. Selectivity for strand-transfer over 3'-processing and susceptibility to clinical resistance of HIV-1 integrase inhibitors are driven by key enzyme-DNA interactions in the active site. Nucleic Acids Res 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

PLOS COMPUTATIONAL BIOLOGY 

Nussinov R, Papin JA. Computing Biology. PLoS Comput Biol 12(7):e1005050, 2016.

PLOS ONE 

Watters SA, Mlcochova P, Maldarelli F, Goonetilleke N, Pillay D, Gupta RK. Sequential CCR5-Tropic HIV-1 Reactivation from Distinct Cellular Reservoirs following Perturbation of Elite Control. PLoS One 11(7):e0158854, 2016.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES 

Imamichi H, Dewar RL, Adelsberger JW, Rehm CA, O'Doherty U, Paxinos EE, Fauci AS, Lane HC. Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy. Proc Natl Acad Sci U S A 113(31):8783-8, 2016.

RETROVIROLOGY

Shao W, Shan J, Kearney MF, Wu X, Maldarelli F, Mellors JW, Luke B, Coffin JM, Hughes SH. Retrovirus Integration Database (RID): a public database for retroviral insertion sites into host genomes. Retrovirology 13(1):47, 2016.

SCIENCE

Gibson BA, Zhang YJ, Jiang H, Hussey KM, Shrimp JH, Lin HN, Schwede F, Yu YH, Kraus WL. Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation. Science 353(6294):45-50, 2016.

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