2014 July

Monomeric CH3: A Small, Stable Antibody Domain with Therapeutic Promise

By Ashley DeVine, Staff WriterPlatinum Highlight Icon

Antibody domains are emerging as promising biopharmaceuticals because of their relatively small size compared to full-sized antibodies, which are too large to effectively penetrate tumors and bind to sterically restricted therapeutic targets.

In an article published in The Journal of Biological Chemistry, Tianlei Ying, Ph.D., Dimiter Dimitrov, Ph.D., and their colleagues in the Protein Interactions Group, Cancer and Inflammation Program, Center for Cancer Research, reported their design of a novel antibody domain, monomeric CH3 (mCH3).

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More than 3,200 Books and DVDs Donated to Annual Book Swap

People searching through books

Robin Meckley, Contributing Writer

The Scientific Library’s 14th Annual Book and Media Swap, held on April 16 in the lobby of Building 549, proved to be a popular event.

When the swap was rescheduled from fall 2013 to spring 2014, the library staff was uncertain if the response would be equal to previous years, said Sue Wilson, principal manager of the Scientific Library. NCI at Frederick employees rose to the challenge, however, with 87 people donating more than 3,200 books and DVDs, according to Pam Noble, serials technician and book swap team leader. By the end of the first day of the swap, almost half of the materials had been claimed.

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Weather Advisory: Tornados

Tornado graphic

Summer months carry the threat of severe storms and tornados in our area. Take a few moments to consider how well you are prepared in the event of a tornado warning.

The time to prepare for a tornado is before it happens. The Federal Emergency Management Agency (FEMA) provides information on how to prepare and what to do in the event of a tornado. Take a few moments to read the important safety information FEMA has assembled: http://www.ready.gov/tornadoes.

Sign Up for Text Alerts from Frederick County

You can also sign up for text alerts to your cell phone from Frederick County at http://www.frederickcountymd.gov/ALERT.

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