Laboratory Animal Sciences Program
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Special Stains

For animal health diagnostic purposes or for specific anatomic or cellular components, Special Stains are performed. PHL performs a wide variety of special stains to assist in diagnostics. A chemical dye (other than the routine hematoxylin and eosin H&E) is applied to tissue sections to demonstrate specific anatomical or cellular components.

Some of the routine special stains performed are:

  • Periodic Acid-Schiff reaction (PAS): demonstrates the presence of glycogen
  • Brown and Hopps Gram stain (B+H): demonstrates the presence of Gram positive and Gram negative organisms
  • Steiner stain: demonstrates the presence of spirochetes
  • Grocott Methenamine Silver (GMS): demonstrates the presence of fungi.
Wrist Joint Beta Gal

Positive and negative controls are included, at no cost to investigator, on all special stains.

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