Skip NavigationSkip to Content
Return Return to Search Results

Grassypeptolides F and G, Cyanobacterial Peptides from Lyngbya majuscula

  1. Author:
    Popplewell, W. L.
    Ratnayake, R.
    Wilson, J. A.
    Beutler, J. A.
    Colburn, N. H.
    Henrich, C. J.
    McMahon, J. B.
    McKee, T. C.

  2. Author Address

    [Popplewell, WL; Ratnayake, R; Wilson, JA; Beutler, JA; Henrich, CJ; McMahon, JB; McKee, TC] NCI Frederick, Mol Targets Lab, Ctr Canc Res, Frederick, MD 21702 USA. [Colburn, NH] NCI, Lab Canc Prevent, Ctr Canc Res, Frederick, MD 21702 USA. [Henrich, CJ] NCI, SAIC Frederick Inc, Frederick, MD 21702 USA.;McKee, TC (reprint author), NCI Frederick, Mol Targets Lab, Ctr Canc Res, Frederick, MD 21702 USA;mckeeta@mail.nih.gov
    1. Year: 2011
    2. Date: Aug
  2. Journal: Journal of Natural Products
    1. 74
    2. 8
    3. Pages: 1686-1691
  4. Type of Article: Article
  5. ISSN: 0163-3864
  1. Abstract:

    Grassypeptolides F (1) and G (2), bis-thiazoline-containing cyclic depsipeptides with a rare beta-amino acid, extensive N-methylation, and a large number of D-amino acids, are reported from an extract of the Palauan cyanobacterium Lyngbya majuscula. Both 1 and 2 were found to have moderate inhibitory activity against the transcription factor AP-1 (IC(50) = 5.2 and 6.0 mu M, respectively).

    See More

  1. Keywords:

External Sources

  1. View Full Text
  2. DOI: 10.1021/np2005083
  3. View record in Web of Science®
  4. WOS: 000294242800002

Library Notes

  1. Fiscal Year: FY2010-2011
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel