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Penicillium citrinum: Opportunistic pathogen or idle bystander? A case analysis with demonstration of galactomannan cross-reactivity.

  1. Author:
    Hesse, Shayla E
    Luethy, Paul M
    Beigel, John
    Zelazny, Adrian M

  2. Author Address

    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Department of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, MD, USA., Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.,
    1. Year: 2017
    2. Date: Sep
    3. Epub Date: 22 May 2017
  2. Journal: Medical mycology case reports
    1. 17
    2. Pages: 8-10
  4. Type of Article: Article
  5. Article Number: 8-10
  6. ISSN: 2211-7539
  1. Abstract:

    We present a case of an immunocompromised woman with fever, pulmonary infiltrates and multiple bronchoalveolar lavage (BAL) cultures positive for Penicillium citrinum with a concomitant high BAL galactomannan level. We report the results of Aspergillus galactomannan testing performed on culture supernatants from her P. citrinum strain that confirmed the suspected cross-reactivity. Finally, we discuss the clinical significance and antifungal susceptibility of P. citrinum in our case and review the literature.

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  1. Keywords:

External Sources

  1. View Full Text
  2. DOI: 10.1016/j.mmcr.2017.05.003
  3. PMID: 28580236
  4. PMCID: PMC5447564
  5. View record in Web of Science®
  6. WOS: 000416068100003

Library Notes

  1. Open Access Publication
  2. Fiscal Year: FY2016-2017
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