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Analysis of Site Heterogeneity and HIV Outcomes Across Rural and Urban Study Sites in Phidisa II - A Multi-site Randomized Controlled Antiretroviral Treatment Trial in a South African Military Cohort

  1. Author:
    Steytler, John
    Shaw, Pamela A.
    Pau, Alice K.
    Khabo, Paul
    Joshi, Gyan
    Oelofse, Pieter

  2. Author Address

    South African Mil Hlth Serv, Project Phidisa, Cape Town, South Africa.Partnership Microbicides, Paarl, South Africa.NIAID, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA.Univ Penn, Philadelphia, PA USA.NIAID, NIH, Bethesda, MD USA.South African Mil Hlth Serv, Project Phidisa, Pretoria, South Africa.SAIC Frederick Inc, NCI Frederick, Frederick, MD USA.
    1. Year: 2017
  2. Journal: Current HIV Research
  3. BENTHAM SCIENCE PUBL LTD,
    1. 15
    2. 3
    3. Pages: 178-187
  5. Type of Article: Article
  6. ISSN: 1570-162X
  1. Abstract:

    Background: Clinical trials frequently enroll subjects from different study sites. Few such studies provide analysis by individual site. Between 2004-2007, the South African Military Health System (SAMHS) established 6 research sites (3 urban, 3 rural) to build capacity for clinical research and HIV care. We explore differences in clinical, virologic and CD4 outcomes by site in the context of a randomized controlled trial.

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External Sources

  1. View Full Text
  2. DOI: 10.2174/1570162X15666170517123910
  3. PMID: 28521717
  4. View record in Web of Science®
  5. WOS: 000405320700004

Library Notes

  1. Fiscal Year: FY2016-2017
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