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Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib

  1. Author:
    Kraft, Ira L.
    Akshintala, Srivandana
    Zhu, Yuelin
    Lei, Haiyan
    Derse-Anthony, Claudia
    Dombi, Eva
    Steinberg, Seth M.
    Lodish, Maya
    Waguespack, Steven G.
    Kapustina, Oxana
    Fox, Elizabeth
    Balis, Frank M.
    Merino, Maria J.
    Meltzer, Paul S.
    Glod, John W.
    Shern, Jack F.
    Widemann, Brigitte C.

  2. Author Address

    NCI, Pediat Oncol Branch, Ctr Canc Res, Bethesda, MD 20892 USA.NYU, Dept Pediat, Langone Med Ctr, New York, NY 10016 USA.NCI, Genet Branch, Ctr Canc Res, Bethesda, MD 20892 USA.Leidos Biomed Res Inc, Clin Monitoring Res Program, Clin Res Directorate, NCI Campus Frederick, Frederick, MD USA.NCI, Biostat & Data Management Sect, Ctr Canc Res, Bethesda, MD 20892 USA.Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Dev Endocrine Oncol & Genet, Bethesda, MD USA.Univ Texas MD Anderson Canc Ctr, Dept Endocrine Neoplasia & Hormonal Disorders, Houston, TX 77030 USA.Harris IT Serv, Clin Res, Sterling, VA USA.Childrens Hosp Philadelphia, Div Oncol, Philadelphia, PA 19104 USA.NCI, Translat Surg Pathol Sect, Ctr Canc Res, Bethesda, MD 20892 USA.
    1. Year: 2018
    2. Date: Feb 15
  2. Journal: CLINICAL CANCER RESEARCH
  3. AMER ASSOC CANCER RESEARCH,
    1. 24
    2. 4
    3. Pages: 753-765
  5. Type of Article: Article
  6. ISSN: 1078-0432
  1. Abstract:

    Purpose: Vandetanib is well-tolerated in patients with advanced medullary thyroid carcinoma (MTC). Long-term outcomes and mechanisms of MTC progression have not been reported previously.

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External Sources

  1. View Full Text
  2. DOI: 10.1158/1078-0432.CCR-17-2101
  3. PMID: 29187393
  4. View record in Web of Science®
  5. WOS: 000425191300005

Library Notes

  1. Fiscal Year: FY2017-2018
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