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Sex-specific gene and pathway modeling of inherited glioma risk

  1. Author:
    Ostrom, Quinn T.
    Coleman, Warren
    Huang, William
    Rubin, Joshua B.
    Lathia, Justin D.
    Berens, Michael E.
    Speyer, Gil
    Liao, Peter
    Wrensch, Margaret R.
    Eckel-Passow, Jeanette E.
    Armstrong, Georgina
    Rice, Terri
    Wiencke, John K.
    McCoy, Lucie S.
    Hansen, Helen M.
    Amos, Christopher I.
    Bernstein, Jonine L.
    Claus, Elizabeth B.
    Houlston, Richard S.
    Il'yasova, Dora
    Jenkins, Robert B.
    Johansen, Christoffer
    Lachance, Daniel H.
    Lai, Rose K.
    Merrell, Ryan T.
    Olson, Sara H.
    Sadetzki, Siegal
    Schildkraut, Joellen M.
    Shete, Sanjay
    Andersson, Ulrika
    Rajaraman, Preetha
    Chanock,Stephen
    Linet, Martha S.
    Wang, Zhaoming
    Yeager, Meredith
    Melin, Beatrice
    Bondy, Melissa L.
    Barnholtz-Sloan, Jill S.
    Freeman, Laura E. Beane
    Koutros, Stella
    Albanes, Demetrius
    Visvanathan, Kala
    Stevens, Victoria L.
    Henriksson, Roger
    Michaud, Dominique S.
    Feychting, Maria
    Ahlbom, Anders
    Giles, Graham G.
    Giles, Graham G.
    Milne, Roger
    McKean-Cowdin, Roberta
    Le Marchand, Loic
    Stampfer, Meir
    Ruder, Avima M.
    Carreon, Tania
    Hallmans, Goran
    Zeleniuch-Jacquotte, Anne
    Gaziano, J. Michael
    Sesso, Howard D.
    Purdue, Mark P.
    White, Emily
    Peters, Ulrike
    Buring, Julie

  2. Author Address

    Case Western Reserve Univ, Sch Med, Case Comprehens Canc Ctr, 11100 Euclid Ave, Cleveland, OH 44106 USA.Baylor Coll Med, Dept Med, Sect Epidemiol & Populat Sci, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA.Case Western Reserve Univ, Sch Med, Dept Populat & Quantitat Hlth Sci, Cleveland, OH USA.Univ Sch, Chagrin Falls, OH USA.Case Western Reserve Univ, Cleveland, OH 44106 USA.Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA.Washington Univ, Sch Med, Dept Neurosci, St Louis, MO USA.Cleveland Clin Fdn, Dept Stem Cell Biol & Regenerat Med, 9500 Euclid Ave, Cleveland, OH 44195 USA.Translat Genom Res Inst, Canc & Cell Biol Div, Phoenix, AZ USA.Univ Calif San Francisco, Sch Med, Dept Neurol Surg, San Francisco, CA USA.Mayo Clin, Coll Med, Div Biomed Stat & Informat, Rochester, MN USA.Baylor Coll Med, Inst Clin & Translat Res, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 USA.Mem Sloan Kettering Canc Ctr, Dept Epidemiol & Biostat, New York, NY 10021 USA.Yale Univ, Sch Publ Hlth, New Haven, CT USA.Brigham & Womens Hosp, Dept Neurosurg, 75 Francis St, Boston, MA 02115 USA.Inst Canc Res, Div Genet & Epidemiol, Sutton, Surrey, England.Georgia State Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Atlanta, GA 30303 USA.Duke Univ, Med Ctr, Dept Community & Family Med, Canc Control & Prevent Program, Durham, NC 27710 USA.Duke Univ, Med Ctr, Duke Canc Inst, Durham, NC USA.Mayo Clin, Ctr Comprehens Canc, Dept Lab Med & Pathol, Rochester, MN USA.Rigshosp, Finsen Ctr, Oncol Clin, Copenhagen, Denmark.Danish Canc Soc, Res Ctr, Survivorship Res Unit, Copenhagen, Denmark.Mayo Clin, Ctr Comprehens Canc, Dept Neurol, Rochester, MN USA.Univ Southern Calif, Keck Sch Med, Dept Neurol, Los Angeles, CA USA.Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA USA.NorthShore Univ HealthSyst, Dept Neurol, Evanston, IL USA.Chaim Sheba Med Ctr, Gertner Inst, Canc & Radiat Epidemiol Unit, Tel Hashomer, Israel.Tel Aviv Univ, Sch Publ Hlth, Dept Epidemiol & Prevent Med, Sackler Fac Med, Tel Aviv, Israel.Univ Virginia, Sch Med, Dept Publ Hlth Sci, Charlottesville, VA 22908 USA.Univ Texas MD Anderson Canc Ctr, Dept Biostat, Houston, TX 77030 USA.Umea Univ, Fac Med, Dept Radiat Sci, Umea, Sweden.NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.NCI, Core Genotyping Facil, SAIC Frederick Inc, Gaithersburg, MD USA.St Jude Childrens Res Hosp, Dept Computat Biol, 332 N Lauderdale St, Memphis, TN 38105 USA.
    1. Year: 2019
    2. Date: JAN
  2. Journal: NEURO-ONCOLOGY
  3. OXFORD UNIV PRESS INC,
    1. 21
    2. 1
    3. Pages: 71-82
  5. Type of Article: Article
  6. ISSN: 1522-8517
  1. Abstract:

    Background To date, genome-wide association studies (GWAS) have identified 25 risk variants for glioma, explaining 30% of heritable risk. Most histologies occur with significantly higher incidence in males, and this difference is not explained by currently known risk factors. A previous GWAS identified sex-specific glioma risk variants, and this analysis aims to further elucidate risk variation by sex using gene- and pathway-based approaches.

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External Sources

  1. View Full Text
  2. DOI: 10.1093/neuonc/noy135
  3. PMID: 30124908
  4. PMCID: PMC6303471
  5. View record in Web of Science®
  6. WOS: 000462586300009

Library Notes

  1. Fiscal Year: FY2018-2019
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