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Multiple Endocrine Neoplasia Type 2B Presents Early in Childhood but Often Is Undiagnosed for Years

  1. Author:
    Makri, Angeliki
    Akshintala, Srivandana
    Derse-Anthony, Claudia
    Widemann, Brigitte
    Stratakis, Constantine A.
    Glod, John
    Lodish, Maya
  2. Author Address

    Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Bethesda, MD USA.NCI, Pediat Oncol Branch, NIH, Bethesda, MD 20892 USA.NYU, Sch Med, Div Pediat Hematol Oncol, New York, NY USA.Leidos Biomed Res Inc, Frederick Natl Lab Canc Res, Clin Monitoring Res Program, Clin Res Directorate, Frederick, MD USA.
    1. Year: 2018
    2. Date: DEC
    3. Epub Date: 2018 10 09
  1. Journal: JOURNAL OF PEDIATRICS
  2. MOSBY-ELSEVIER,
    1. 203
    2. Pages: 447-449
  3. Type of Article: Article
  4. ISSN: 0022-3476
  1. Abstract:

    We describe the presenting symptoms and signs of multiple endocrine neoplasia type 2B in a cohort of children. Improved awareness of the early nonendocrine signs of multiple endocrine neoplasia type 2B could lead to earlier diagnosis before the development of medullary thyroid cancer and possibly its metastasis.

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External Sources

  1. DOI: 10.1016/j.jpeds.2018.08.022
  2. PMID: 30314660
  3. WOS: 000450636400066

Library Notes

  1. Fiscal Year: FY2018-2019
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