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The promise of comparative genomics in mammals

  1. Author:
    O'Brien, S. J.
    Menotti-Raymond, M.
    Murphy, W. J.
    Nash, W. G.
    Wienberg, J.
    Stanyon, R.
    Copeland, N. G.
    Jenkins, N. A.
    Womack, J. E.
    Graves, J. A. M.

  2. Author Address

    O'Brien SJ NCI, Lab Genom Divers Frederick, MD 21702 USA NCI, Lab Genom Divers Frederick, MD 21702 USA NCI, Mammalian Genet Lab, Adv Biosci Labs Frederick, MD 21702 USA Texas A&M Univ, Coll Vet Med, Dept Vet Pathol College Stn, TX 77843 USA La Trobe Univ, Dept Genet & Evolut Melbourne Vic 3083 Australia
    1. Year: 1999
  2. Journal: Science
    1. 286
    2. 5439
    3. Pages: 458-+
  4. Type of Article: Review
  1. Abstract:

    Dense genetic maps of human, mouse, and rat genomes that are based on coding genes and on microsatellite and single-nucleotide polymorphism markers have been complemented by precise gene homolog alignment with moderate-resolution maps of Livestock, companion animals, and additional mammal species. Comparative genetic assessment expands the utility of these maps in gene discovery, in functional genomics, and in tracking the evolutionary forces that sculpted the genome organization of modern mammalian species. [References: 203]

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