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A guide to naming human non-coding RNA genes

  1. Author:
    Seal, Ruth L.
    Chen, Ling-Ling
    Griffiths-Jones, Sam
    Lowe, Todd M.
    Mathews, Michael B.
    O'Reilly, Dawn
    Pierce, Andrew J.
    Stadler, Peter F.
    Ulitsky, Igor
    Wolin,Sandra
    Bruford, Elspeth A.
  2. Author Address

    Univ Cambridge, Dept Haematol, Sch Clin Med, Cambridge, England.European Bioinformat Inst, European Mol Biol Lab, Hinxton, England.Chinese Acad Sci, Shanghai Inst Biochem & Cell Biol, State Key Lab Mol Biol, Shanghai, Peoples R China.Univ Manchester, Sch Biol Sci, Fac Biol Med & Hlth, Manchester, Lancs, England.Univ Calif Santa Cruz, Dept Biomol Engn, Santa Cruz, CA 95064 USA.Rutgers New Jersey Med Sch, Dept Med, Newark, NJ USA.Univ Oxford, MRC CRUK Oxford Inst, Computat Biol & Integrat Genom Lab, Oxford, England.Univ Oxford, Dept Oncol, Oxford, England.AstraZeneca, Translat Med Oncol R&D, Cambridge, England.Univ Leipzig, Interdisciplinary Ctr Bioinformat, Dept Comp Sci, Bioinformat Grp, Leipzig, Germany.Max Planck Inst Math Sci, Leipzig, Germany.Univ Vienna, Inst Theoret Chem, Vienna, Austria.Univ Nacl Colombia, Fac Ciencias, Bogota, Colombia.Santa Fe Inst, Santa Fe, NM 87501 USA.Weizmann Inst Sci, Dept Regulat Biol, Rehovot, Israel.NCI, RNA Biol Lab, NIH, Frederick, MD 21701 USA.
    1. Year: 2020
    2. Date: Mar 16
    3. Epub Date: 2020 02 24
  1. Journal: The EMBO journal
  2. WILEY,
    1. 39
    2. 6
  3. Type of Article: Review
  4. Article Number: e103777
  5. ISSN: 0261-4189
  1. Abstract:

    Research on non-coding RNA (ncRNA) is a rapidly expanding field. Providing an official gene symbol and name to ncRNA genes brings order to otherwise potential chaos as it allows unambiguous communication about each gene. The HUGO Gene Nomenclature Committee (HGNC, ) is the only group with the authority to approve symbols for human genes. The HGNC works with specialist advisors for different classes of ncRNA to ensure that ncRNA nomenclature is accurate and informative, where possible. Here, we review each major class of ncRNA that is currently annotated in the human genome and describe how each class is assigned a standardised nomenclature.

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External Sources

  1. DOI: 10.15252/embj.2019103777
  2. PMID: 32090359
  3. PMCID: PMC7073466
  4. WOS: 000515136000001

Library Notes

  1. Fiscal Year: FY2019-2020
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