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Craniofacial Development Is Fine-Tuned by Sox2

  1. Author:
    Mandalos, Nikolaos Panagiotis
    Dimou, Aikaterini
    Gavala, Maria Angeliki
    Lambraki, Efstathia
    Remboutsika, Eumorphia [ORCID]
  2. Author Address

    University Research Institute of Maternal and Child Health & Precision Medicine, School of Medicine, National and Kapoditrian University of Athens, 115 27 Athens, Greece., National Cancer Institute, Frederick, MD 21702, USA., Center for Translational Medicine and the Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., National Technical University of Athens, 157 80 Athens, Greece., Polytechnic School, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece., Thrivus Institute for Biomedical Science and Technology, Constellations Ave, Accra GT-336-4330, Ghana.,
    1. Year: 2023
    2. Date: Jan 31
    3. Epub Date: 2023 01 31
  1. Journal: Genes
    1. 14
    2. 2
  2. Type of Article: Article
  3. Article Number: 380
  1. Abstract:

    The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals that control these complex developmental processes.

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External Sources

  1. DOI: 10.3390/genes14020380
  2. PMID: 36833308
  3. PMCID: PMC9956624
  4. PII : genes14020380

Library Notes

  1. Fiscal Year: FY2022-2023
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