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New chondropsin macrolide lactams from marine sponges in the genus Ircinia

  1. Author:
    Rashid, M. A.
    Gustafson, K. R.
    Boyd, M. R.

  2. Author Address

    NCI, Div Basic Sci, Lab Drug Discovery Res & Dev, Room 121, Frederick, MD 21702 USA. NCI, Div Basic Sci, Lab Drug Discovery Res & Dev, Frederick, MD 21702 USA. SAIC Frederick, Frederick, MD 21702 USA. Boyd MR NCI, Div Basic Sci, Lab Drug Discovery Res & Dev, Room 121, Frederick, MD 21702 USA.
    1. Year: 2001
  2. Journal: Tetrahedron Letters
    1. 42
    2. 9
    3. Pages: 1623-1626
  4. Type of Article: Article
  1. Abstract:

    Two new polyketide-derived macrolide lactams, identified as 73- deoxychondropsin A (2) and chondropsin C (3), have been isolated from two different collections of marine sponges which belong to the genus 6 Ircinia. An Australian collection of Ircinia ramosa provided 73-deoxychondropsin A (2), while samples of Ircinia sp. collected in the Philippines yielded chondropsin C (3). The structures of 2 and 3 were assigned by interpretation of their spectral data. Published by Elsevier Science Ltd.

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