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The role of growth hormone in T-cell development and reconstitution

  1. Author:
    Welniak, L. A.
    Sun, R.
    Murphy, W. J.

  2. Author Address

    NCI, SAIC, Intramural Res Support Program, Bldg 567, Room 210, Frederick, MD 21702 USA. NCI, SAIC, Intramural Res Support Program, Frederick, MD 21702 USA. NCI, Immunoregulat Lab, Frederick, MD 21702 USA. Murphy WJ NCI, SAIC, Intramural Res Support Program, Bldg 567, Room 210, Frederick, MD 21702 USA.
    1. Year: 2002
  2. Journal: Journal of Leukocyte Biology
    1. 71
    2. 3
    3. Pages: 381-387
  4. Type of Article: Review
  1. Abstract:

    Growth hormone (GH), directly or through GH-induction of insulin-like growth factor (IGF)-1, has been implicated in lymphocyte development and function. Recent studies have questioned the role of GH and IGF-1 in immune responses. This review examines experimental data describing the immunoregulatory function of GH and attempts to reconcile the literature.

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