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Preparation and reactivity of O-2-sulfonated diazeniumdiolates

  1. Author:
    D'Sa, R. A.
    Wang, Y. H.
    Ruane, P. H.
    Showalter, B. M.
    Saavedra, J. E.
    Davies, K. M.
    Citro, M. L.
    Booth, M. N.
    Keefer, L. K.
    Toscano, J. P.
  2. Author Address

    Johns Hopkins Univ, Dept Chem, 3400 N Charles St, Baltimore, MD 21218 USA Johns Hopkins Univ, Dept Chem, Baltimore, MD 21218 USA NCI, Chem Sect, Comparat Carcinogenesis Lab, Frederick, MD 21702 USA George Mason Univ, Dept Chem, Fairfax, VA 22030 USA NCI, Basic Res Program, SAIC Frederick, Frederick, MD 21702 USA Toscano JP Johns Hopkins Univ, Dept Chem, 3400 N Charles St, Baltimore, MD 21218 USA
    1. Year: 2003
  1. Journal: Journal of Organic Chemistry
    1. 68
    2. 2
    3. Pages: 656-657
  2. Type of Article: Article
  1. Abstract:

    We report the facile preparation of O-2-sulfonated diazeniumdiolates and mechanistic investigation of their reactions with representative nucleophiles. This new class of compounds extends the range of O-2-substituted diazeniumdiolates available for potential applications in research and medicine.

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