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Cellular Proteins in Hiv Virions

  1. Author:
    Ott, D. E.

  2. Author Address

    Ott DE NCI FREDERICK CANC RES & DEV CTR SAIC FREDERICK AIDS VACCINE PROGRAM FREDERICK, MD 21702 USA
    1. Year: 1997
  2. Journal: Reviews in Medical Virology
    1. 7
    2. 3
    3. Pages: 167-180
  4. Type of Article: Review
  1. Abstract:

    Human immunodeficiency virus type-1 (HIV-I) virions contain both virus-encoded and cellular proteins. Recent advances in the detection, isolation, and functional characterisation of host proteins incorporated in the virion have begun to provide for new perspectives on the interactions between virus and cell. The acquisition of host proteins by HIV-I may also influence viral pathology in vivo. This article reviews detection and analysis of host proteins found in HIV-1 particles and presents some potential roles that these proteins might play in the biology of this important virus. (C) 1997 by John Wiley & Sons, Ltd. [References: 67]

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