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Angiogenesis as an immunopharmacologic target in inflammation and cancer

  1. Author:
    Bian, X. W.
    Chen, J. H.
    Jiang, X. F.
    Bai, J. S.
    Wang, Q. L.
    Zhang, X.

  2. Author Address

    Third Mil Med Univ, SW Hosp, Inst Pathol, Chongqing 400038, Peoples R China. NCI, Expt Immunol Lab, Canc Res Ctr, Frederick, MD 21702 USA Bian, XW, Third Mil Med Univ, SW Hosp, Inst Pathol, Chongqing 400038, Peoples R China
    1. Year: 2004
    2. Date: NOV
  2. Journal: International Immunopharmacology
    1. 4
    2. 12
    3. Pages: 1537-1547
  4. Type of Article: Article
  1. Abstract:

    Many pathological processes including wound healing, chronic inflammation and cancer require angiogenesis, i.e., the formation of new vasculature in the lesions. Accumulating evidence indicates that angiogenesis is crucial for both chronic inflammation and the growth of malignant tumors with the participation of diverse cytokines, chemokines and growth factors. It is nevertheless believed that differences exist in angiogenesis between cancer and chronic inflammatory diseases. The aim of this review is to outline the characteristics of angiogenesis in chronic inflammation and cancer. A better understanding of the angiogenic processes may facilitate the design of more effective therapies for chronic inflammation and cancer. (C) 2004 Elsevier B.V. All rights reserved

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External Sources

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  2. DOI: 10.1016/j.intimp.2004.07.017
  3. View record in Web of Science®
  4. WOS: 000224133000011

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