Skip NavigationSkip to Content
Return Return to Search Results

Efficacy and safety of generic amphotericin B in experimental pulmonary aspergillosis

  1. Author:
    Petraitis, V.
    Petraitiene, R.
    Lin, P. X.
    Calis, K.
    Kelaher, A. M.
    Muray, H. A.
    Mya-San, C.
    Mickiene, D.
    Bacher, J.
    Walsh, T. J.

  2. Author Address

    NCI, Pediat Oncol Branch, Immunocompromised Host Sect, CRC, Bethesda, MD 20892 USA. NIH, Surg Serv, Vet Resources Program, Off Res Serv, Bethesda, MD USA. Warren Grant Magnuson Clin Ctr, Dept Pharm, Bethesda, MD USA. SAIC Frederick Inc, Frederick, MD USA Walsh, TJ, NCI, Pediat Oncol Branch, Immunocompromised Host Sect, CRC, Bldg 10,Rm 1W-5740,10 Ctr Dr,MSC 1100, Bethesda, MD 20892 USA
    1. Year: 2005
  2. Journal: Antimicrobial Agents and Chemotherapy
    1. 49
    2. 4
    3. Pages: 1642-1645
  4. Type of Article: Article
  1. Abstract:

    The recent shortage of the brand name drug Fungizone has necessitated a change to generic formulations of amphotericin B deoxycholate. Clinical trials cannot be conducted in a timely manner to provide data on the safety and efficacy of these formulations. We therefore compared generic amphotericin B and Fungizone for activity and safety in the treatment of experimental invasive pulmonary aspergillosis (IPA) in persistently neutropenic rabbits. Fungizone and generic amphotericin B are similar in efficacy, pharmacokinetics, and safety in the treatment of experimental IPA

    See More

  1. Keywords:

External Sources

  1. View record in Web of Science®
  2. WOS: 000228082500065

Library Notes

  1. No notes added.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel