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Galactoxylomannan does not exhibit cross-reactivity in the Platelia Aspergillus enzyme immunoassay

  1. Author:
    De Jesus, M.
    Hackett, E.
    Durkin, M.
    Connolly, P.
    Casadevall, A.
    Petraitiene, R.
    Walsh, T. J.
    Wheat, L. J.

  2. Author Address

    MiraVista Diagnost, Indianapolis, IN 46241 USA. Yeshiva Univ Albert Einstein Coll Med, Bronx, NY 10461 USA. NCI, CRC, Immunocompromised Host Sect, Pediat Oncol Branch, Bethesda, MD 20892 USA. SAIC Frederick Inc, Lab Anim Sci Program, Frederick, MD 21702 USA.;Wheat, LJ, MiraVista Diagnost, 4444 Decatur Blvd,Suite 300, Indianapolis, IN 46241 USA.;jwheat@miravistalabs.com
    1. Year: 2007
    2. Date: May
  2. Journal: Clinical and Vaccine Immunology
    1. 14
    2. 5
    3. Pages: 624-627
  4. Type of Article: Article
  5. ISSN: 1556-6811
  1. Abstract:

    Given the recent report of a false-positive result in the Platelia Aspergillus enzyme immunoassay in a patient with cryptococcosis and in yeast extracts and purified galactoxylomannan of Cryptococcus neoformans, we evaluated culture extracts, purified polysaccharides, clinical specimens, and specimens from animals following experimental infection. Our results revealed no cross-reactions.

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External Sources

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  2. DOI: 10.1128/cvi.00368-06
  3. View record in Web of Science®
  4. WOS: 000246681800019

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