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Seroprevalence and risk factors for human herpesvirus 8 infection, rural egypt

  1. Author:
    Mbulaiteye, S. M.
    Pfeiffer, R. M.
    Dolan, B.
    Tsang, V.
    Noh, J.
    Mikhail, N.
    Abdel-Hamid, M.
    Hashem, M.
    Whitby, D.
    Strickl, G. T.
    Goedert, J. J.

  2. Author Address

    Mbulaiteye, Sam M.; Pfeiffer, Ruth M.; Dolan, Bryan, Goedert, James J.] NCI, Rockville, MD USA. [Whitby, Denise] NCI, Frederick, MD 21701 USA. [Abdel-Hamid, Mohamed, Hashem, Mohamed, Strickland, G. Thomas] Univ Maryland, Sch Med, Baltimore, MD 21201 USA. [Abdel-Hamid, Mohamed, Hashem, Mohamed] Natl Hepatol & Trop Med Res Inst, Cairo, Egypt. [Tsang, Victor C. W.; Noh, John] Ctr Dis Control & Prevent, Atlanta, GA USA. [Mikhail, Nabiel N. H.] Assiut Univ, Cairo, Egypt.
    1. Year: 2008
  2. Journal: Emerging Infectious Diseases
    1. 14
    2. 4
    3. Pages: 586-591
  4. Type of Article: Proceedings Paper
  1. Abstract:

    To determine whether human herpesvirus 8 (HHV-8) is associated with schistosomal and hepatitis C virus infections in Egypt, we surveyed 965 rural household participants who had been tested for HHV-8 and schistosomal infection (seroprevalence 14.2% and 68.6%, respectively, among those <15 years of age, and 24.2% and 72.8%, respectively, among those 2:15 years of age). Among adults, HHV-8 seropositivity was associated with higher age, lower education, dental treatment, tattoos, >10 lifetime injections, and hepatitis C virus seropositivity. In adjusted analyses, HHV-8 seropositivity was associated with dental treatment among men (odds ratio [OR] 2.4, 95% confidence interval [CI] 1.1-5.2) and hepatitis C virus seropositivity among women (OR 3.3, 95% Cl 1.4-7.9). HHV-8 association with antischistosomal antibodies was not significant for men (OR 2.1, 95% CI 0.3-16.4), but marginal for women (OR 1.5, 95% Cl 1.0-2.5). Our findings suggest salivary and possible nosocomial HHV-8 transmission in rural Egypt.

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External Sources

  1. PMID: 18394276

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