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Alarmins and antimicrobial immunity

  1. Author:
    Yang, D.
    Oppenheim, J. J.

  2. Author Address

    Basic Research Program, SAIC-Frederick, Inc., Center for Cancer Research, National Cancer Institute at Frederick, National Institute of Health, 1050 Boyles Street, Frederick, MD 21702-1201, USA. dyang@ncifcrf.gov
    1. Year: 2009
    2. Epub Date: 3/3/2009
  2. Journal: Medical Mycology
    1. 47
    2. Suppl 1
    3. Pages: S146-53
  4. Type of Article: Review
  5. ISSN: 1460-2709 (Electronic)
  1. Abstract:

    Alarmins are endogenous mediators capable of enhancing innate and adaptive immune response through induction of concomitant recruitment and activation of antigen-presenting cells. Here we provide a brief overview of various alarmins, highlight their critical roles in innate and adaptive antimicrobial immunity, and speculate on potential usage of alarmins in combating aspergillosis.

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External Sources

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  2. DOI: 10.1080/13693780902721416
  3. PMID: 19253139

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