Skip NavigationSkip to Content
Return Return to Search Results

Materials from peptide assembly: towards the treatment of cancer and transmittable disease

  1. Author:
    Branco, M. C.
    Sigano, D. M.
    Schneider, J. P.

  2. Author Address

    [Branco, MC; Sigano, DM; Schneider, JP] NCI, Biol Chem Lab, NIH, Frederick, MD 21702 USA;Schneider, JP (reprint author), NCI, Biol Chem Lab, NIH, Frederick, MD 21702 USA;Joel.Schneider@nih.gov
    1. Year: 2011
    2. Date: Jun
  2. Journal: Current Opinion in Chemical Biology
    1. 15
    2. 3
    3. Pages: 427-434
  4. Type of Article: Review
  5. ISSN: 1367-5931
  1. Abstract:

    As the prevalence of cancer and transmittable disease persists, the development of new and more advanced therapies remains a priority in medical research. An emerging platform for the treatment of these illnesses is the use of materials formed via peptide assembly where the bulk material itself acts as the therapeutic. Higher ordered peptide structures with defined chemistry are capable of cellular targeting, recognition, and internalization. Recent design efforts are being made to exploit the nanoscale definition of the materials formed by assembling peptides to target cancer and microbial cells and to function as vaccines. This review focuses on assembled peptide materials that actively participate in the biological processes important to cancer and transmittable diseases to exert an anticipated functional outcome.

    See More

  1. Keywords:

External Sources

  1. View Full Text
  2. DOI: 10.1016/j.cbpa.2011.03.021
  3. View record in Web of Science®
  4. WOS: 000292434900013

Library Notes

  1. Fiscal Year: FY2010-2011
NCI at FrederickClose Button

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel