Skip NavigationSkip to Content
Return Return to Search Results

In vivo anti-HIV activity of (+)-calanolide A in the hollow fiber mouse model

  1. Author:
    Xu, Z. Q.
    Hollingshead, M. G.
    Borgel, S.
    Elder, C.
    Khilevich, A.
    Flavin, M. T.

  2. Author Address

    Xu ZQ MediChem Res Inc 12305 S New Ave Lemont, IL 60439 USA MediChem Res Inc Lemont, IL 60439 USA Sarawak MediChem Pharmaceut Inc Lemont, IL 60439 USA NCI, Frederick Canc Res & Dev Ctr, Div Canc Treatment & Diagnost, Biol Testing Branch,Dev Therapeut Program,SAIC Frederick, MD 21701 USA
    1. Year: 1999
  2. Journal: Bioorganic & Medicinal Chemistry Letters
    1. 9
    2. 2
    3. Pages: 133-138
  4. Type of Article: Article
  1. Abstract:

    In vivo anti-HIV efficacy of(+)-calanolide A has been evaluated in a hollow fiber mouse model. It was demonstrated that the compound was capable of suppressing virus replication in two distinct and separate physiologic compartments (ip and sc) following oral or parenteral administration on a once- or twice-daily treatment schedule. A synergistic effect was observed for the combination of(+)-calanolide A and AZT. (C) 1999 Elsevier Science Ltd. All rights reserved. [References: 20]

    See More

  1. Keywords:

External Sources

  1. No sources found.

Library Notes

  1. No notes added.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel