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Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI

  1. Author:
    Kreimer, Aimée R
    Chaturvedi, Anil K
    Alemany, Laia
    Anantharaman, Devasena
    Bray, Freddie
    Carrington,Mary
    Doorbar, John
    D'Souza, Gypsyamber
    Fakhry, Carole
    Ferris, Robert L
    Gillison, Maura
    Neil Hayes, D
    Hildesheim, Allan
    Huang, Shao Hui
    Kowalski, Luiz P
    Lang Kuhs, Krystle A
    Lewis, James
    Lowy, Douglas R
    Mehanna, Hisham
    Ness, Andy
    Pawlita, Michael
    Pinheiro, Maisa
    Schiller, John
    Shiels, Meredith S
    Tota, Joseph
    Mirabello, Lisa
    Warnakulasuriya, Saman
    Waterboer, Tim
    Westra, William
    Chanock, Stephen
    Brennan, Paul

  2. Author Address

    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: kreimera@mail.nih.gov., Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: chaturva@mail.nih.gov., Catalan Institute of Oncology (ICO), IDIBELL, L 39;Hospitalet de Llobregat, Barcelona, Spain; Epidemiology and Public Health, Centro de Investigaci 243;n Biom 233;dica en Red: Epidemiolog 237;a y Salud P 250;blica (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: lalemany@iconcologia.net., Rajiv Gandhi Centre for Biotechnology, Trivandrum, India. Electronic address: devasena@rgcb.res.in., International Agency for Research on Cancer, Lyon, France. Electronic address: Brayf@iarc.fr., Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States. Electronic address: carringm@mail.nih.gov., University of Cambridge, Cambridge, United Kingdom. Electronic address: jd121@cam.ac.uk., Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States. Electronic address: Gdsouza2@jhu.edu., Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, United States. Electronic address: cfakhry@jhmi.edu., UPMC Hillman Cancer Center, Pittsburgh, PA, United States. Electronic address: ferrrl@upmc.edu., The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address: mgillison@mdanderson.org., The University of Tennessee Health Science Center, Memphis, TN, United States. Electronic address: Neil.Hayes@uthsc.edu., Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: hildesha@exchange.nih.gov., University of Toronto, Princess Margaret Hospital, Toronto, Ontario, Canada. Electronic address: ShaoHui.Huang@rmp.uhn.ca., A.C. Camargo Cancer Center, S 227;o Paulo, Brazil. Electronic address: lp_kowalski@uol.com.br., Vanderbilt University Medical Center, Nashville, TN, United States. Electronic address: krystle.kuhs@vumc.org., Vanderbilt University Medical Center, Nashville, TN, United States. Electronic address: james.lewis@vanderbilt.edu., Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States; Office of the Director, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: lowyd@mail.nih.gov., Institute for Head and Neck Studies and Education, University of Birmingham, Birmingham, United Kingdom. Electronic address: h.mehanna@bham.ac.uk., NIHR Bristol Biomedical Research Centre, University of Bristol NHS Foundation Trust and University of Bristol, Bristol, United Kingdom. Electronic address: Andy.Ness@bristol.ac.uk., German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: m.pawlita@dkfz-heidelberg.de., Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: maisa.pinheiro@nih.gov., Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: schillej@dc37a.nci.nih.gov., Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: shielsms@mail.nih.gov., Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: joseph.tota@nih.gov., Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: mirabellol@mail.nih.gov., King 39;s College London, London, United Kingdom; WHO Collaborating Centre for Oral Cancer, United Kingdom. Electronic address: saman.warne@kcl.ac.uk., German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: T.Waterboer@dkfz-heidelberg.de., Icahn School of Medicine at Mount Sinai, New York, NY, United States. Electronic address: william.westra@mountsinai.org., Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: hanocks@mail.nih.gov., International Agency for Research on Cancer, Lyon, France. Electronic address: gep@iarc.fr.,
    1. Year: 2020
    2. Date: SEP
    3. Epub Date: 2020 06 02
  2. Journal: Oral oncology
    1. 108
    2. Pages: 104736
  4. Type of Article: Article
  5. Article Number: 104736
  6. ISSN: 1368-8375
  1. Abstract:

    Cancer of the oropharynx has attracted considerable attention in recent years given: (1) an increasing incidence in selected populations over the past three decades; (2) the discovery of human papillomavirus (HPV) infection as the driver of the increase, as opposed to the traditional risk factors such as tobacco (smoking and chewing) and alcohol; and (3) the promise of new prevention and treatment strategies. As a result of such developments, the International Agency for Research on Cancer (IARC) and the US National Cancer Institute (NCI), convened the fourth Cancer Seminar meeting in November 2018 to focus on this topic. This report summarizes the proceedings: a review of recent science on the descriptive epidemiology, etiology, biology, genetics, early detection, pathology and treatment of HPV-positive oropharyngeal cancer, and the formulation of key research questions to be addressed. Published by Elsevier Ltd.

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External Sources

  1. View Full Text
  2. DOI: 10.1016/j.oraloncology.2020.104736
  3. PMID: 32502860
  4. View record in Web of Science®
  5. WOS: 000566724700003
  6. PII : S1368-8375(20)30172-X

Library Notes

  1. Fiscal Year: FY2019-2020
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