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Covid-19.bioreproducibility.org: A web resource for SARS-CoV-2-related structural models

  1. Author:
    Brzezinski, Dariusz
    Kowiel, Marcin
    Cooper, David R
    Cymborowski, Marcin
    Grabowski, Marek
    Wlodawer,Alexander
    Dauter,Zbigniew
    Shabalin, Ivan G
    Gilski, Miroslaw
    Rupp, Bernhard
    Jaskolski, Mariusz [ORCID]
    Minor, Wladek [ORCID]
  2. Author Address

    Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA., Center for Biocrystallographic Research, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland., Institute of Computing Science, Poznan University of Technology, Poznan, Poland., Macromolecular Crystallography Laboratory, National Cancer Institute, Frederick, Maryland, USA., Department of Crystallography, Faculty of Chemistry, A. Mickiewicz University, Poznan, Poland., k.-k. Hofkristallamt, San Diego, California, USA., Division of Genetic Epidemiology, Medical University Innsbruck, Austria.,
    1. Year: 2020
    2. Date: OCT 8
    3. Epub Date: 2020 09 27
  1. Journal: Protein science : a publication of the Protein Society
  2. Type of Article: Article
  3. ISSN: 0961-8368
  1. Abstract:

    The COVID-19 pandemic has triggered numerous scientific activities aimed at understanding the SARS-CoV-2 virus and ultimately developing treatments. Structural biologists have already determined hundreds of experimental X-ray, cryo-EM, and NMR structures of proteins and nucleic acids related to this coronavirus, and this number is still growing. To help biomedical researchers, who may not necessarily be experts in structural biology, navigate through the flood of structural models, we have created an online resource, covid19.bioreproducibility.org, that aggregates expert-verified information about SARS-CoV-2-related macromolecular models. In this paper, we describe this web resource along with the suite of tools and methodologies used for assessing the structures presented therein. This article is protected by copyright. All rights reserved. © 2020 The Protein Society.

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External Sources

  1. DOI: 10.1002/pro.3959
  2. PMID: 32981130
  3. WOS: 000575956600001

Library Notes

  1. Fiscal Year: FY2020-2021
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