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Radiological and functional evidence of the bronchial spread of tuberculosis: an observational analysis

  1. Author:
    Chen, Ray Y.
    Yu, Xiang
    Smith, Bronwyn
    Liu, Xin
    Gao, Jingcai
    Diacon, Andreas H.
    Dawson, Rodney
    Tameris, Michele
    Zhu, Hong
    Qu, Yahong
    Zhang, Ruanqing
    Pan, Shouguo
    Jin, Xiaowei
    Goldfeder, Lisa C.
    Cai, Ying
    Arora, Kriti
    Wang, Jing
    Vincent, Joel
    Malherbe, Stephanus
    Thienemann, Friedrich
    Wilkinson, Robert J.
    Walzl, Gerhard
    Barry, Clifton E.

  2. Author Address

    NIAID, TB Res Sect, Lab Clin Immunol & Microbiol, Div Intramural Res,NIH, Bethesda, MD USA.Wellcome Ctr Infect Dis Res Africa, Brentford, England.Inst Infect Dis & Mol Med, Cape Town, South Africa.Univ Cape Town, Lung Inst, Dept Med, Div Pulmonol, Cape Town, South Africa.Dept Med, Fac Hlth Sci, Cape Town, South Africa.South AfricanTb Vaccine Initiat, Cape Town, South Africa.Univ Cape Town, Cape Town, South Africa.DST NRF Ctr, Excellence Biomed TB Res, South African Med Res Council Ctr, Div Mol Biol & Human Genet,Dept Biomed Sci,Fac Me, Cape Town, South Africa.Dept Med, Cape Town, South Africa.Univ Stellenbosch, Cape Town, South Africa.Henan Prov Chest Hosp, Zhengzhou, Henan, Peoples R China.Sino US TB Collaborat Res Program, Zhengzhou, Henan, Peoples R China.TASK, Appl Sci, Cape Town, South Africa.Kaifeng City Inst TB Prevent & Control, Kaifeng, Henan, Peoples R China.Kaifeng City Inst TB Prevent & Control, Xinxiang, Henan, Peoples R China.Inst TB Prevent & Control, Xinxiang, Henan, Peoples R China.Zhongmu Cty Hlth & Epidem Prevent Stn, Zhongmu, Henan, Peoples R China.Zhongmu Cty Hlth & Epidem Prevent Stn, Xinmi, Henan, Peoples R China.City Inst TB Prevent & Control, Xinmi, Henan, Peoples R China.Clin Monitoring Res Program Directorate, Frederick, MD USA.Univ Zurich Hosp, Dept Internal Med, Zurich, Switzerland.Univ Zurich, Zurich, Switzerland.Francis Crick Inst, London, England.Imperial Coll London, Dept Infect Dis, London, England.
    1. Year: 2021
    2. Date: Oct
  2. Journal: Lancet Microbe
  3. ELSEVIER
    1. 2
    2. 10
    3. Pages: E518-E526
  5. Type of Article: Article
  6. ISSN: 2666-5247
  1. Abstract:

    Background Direct bronchial spread of tuberculosis was extensively described in pre-antibiotic human pathology literature but this description has been overlooked in the post-antibiotic era, in which most pathology data come from animal models that emphasise the granuloma. Modern techniques, such as [F-18]2-fluoro-2-deoxy-D-glucose (FDG) PET-CT scans, might provide further insight. Our aim was to understand normal early tuberculosis resolution patterns on pulmonary PET-CT scans in treated patients with tuberculosis who were subsequently cured.

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External Sources

  1. View Full Text
  2. DOI: 10.1016/S2666-5247(21)00058-6
  3. PMID: 34617068
  4. PMCID: PMC8478663
  5. View record in Web of Science®
  6. WOS: 000704457300011

Library Notes

  1. Fiscal Year: FY2021-2022
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