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The role of dendritic cells in neurodegenerative diseases

  1. Author:
    Iribarren, P.
    Cui, Y. H.
    Le, Y. Y.
    Wang, J. M.
  2. Author Address

    NCI, Mol Immunoregulat Lab, Ctr Canc Res, Bldg 560,Room 31-40, Frederick, MD 21702 USA NCI, Mol Immunoregulat Lab, Ctr Canc Res, Frederick, MD 21702 USA Iribarren P NCI, Mol Immunoregulat Lab, Ctr Canc Res, Bldg 560,Room 31-40, Frederick, MD 21702 USA
    1. Year: 2002
  1. Journal: Archivum Immunologiae et Therapiae Experimentalis
    1. 50
    2. 3
    3. Pages: 187-196
  2. Type of Article: Review
  1. Abstract:

    Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs) involved in the induction of adaptive immune responses. The presence of DCs in the central nervous system (CNS) and the active participation of the immune system in a variety of neurodegenerative diseases have been demonstrated. This review will discuss recent findings pertinent to DCs and other antigen-presenting cells in the CNS in health and disease states.

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