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Myriastramides A-C, new modified cyclic peptides from the Philippines marine sponge Myriastra clavosa

  1. Author:
    Erickson, K. L.
    Gustafson, K. R.
    Milanowski, D. J.
    Pannell, L. K.
    Klose, J. R.
    Boyd, M. R.

  2. Author Address

    NCI, Ctr Canc Res, Mol Targets Dev Program, Bldg 1052,Rm 121, Ft Detrick, MD 21702 USA NCI, Ctr Canc Res, Mol Targets Dev Program, Ft Detrick, MD 21702 USA NIDDKD, Bioorgan Chem Lab, Bethesda, MD 20892 USA SAIC Frederick Inc, NCI Frederick, Analyt Chem Lab, Ft Detrick, MD 21702 USA Univ S Alabama, Coll Med, USA Canc Res Inst, Mobile, AL 36688 USA Gustafson KR NCI, Ctr Canc Res, Mol Targets Dev Program, Bldg 1052,Rm 121, Ft Detrick, MD 21702 USA
    1. Year: 2003
  2. Journal: Tetrahedron
    1. 59
    2. 51
    3. Pages: 10231-10238
  4. Type of Article: Article
  1. Abstract:

    Chemical investigation of the Philippines marine sponge Myriastra clavosa has resulted in the isolation of three new cyclic octapeptides, myriastramides A (1), B (2), and C (3). The structures of compounds 1-3 were assigned based on extensive NMR spectroscopic analyses and a series of degradation and derivatization studies. (C) 2003 Elsevier Ltd. All rights reserved.

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