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The SARS-CoV S glycoprotein

  1. Author:
    Xiao, X.
    Dimitrov, D. S.
  2. Author Address

    NCI, Prot Interact Grp, LECB, CCR,NIH, Frederick, MD 21702 USA Dimitrov, DS, NCI, Prot Interact Grp, LECB, CCR,NIH, Bldg 469,Room 105, Frederick, MD 21702 USA
    1. Year: 2004
    2. Date: OCT
  1. Journal: Cellular and Molecular Life Sciences
    1. 61
    2. 19-20
    3. Pages: 2428-2430
  2. Type of Article: Article
  1. Abstract:

    The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike ( S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. Recent rapid advances in our knowledge of the structure and function of this protein have lead to the development of a number of candidate vaccine immunogens and SARS-CoV entry inhibitors

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External Sources

  1. WOS: 000224888600002

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