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Homologous recombination is promoted by translesion polymerase Pol eta

  1. Author:
    Rattray, A. J.
    Strathern, J. N.

  2. Author Address

    NCI, Gene Regulat & Chromosome Biol Lab, Frederick, MD 21702 USA Rattray, AJ, NCI, Gene Regulat & Chromosome Biol Lab, POB B, Frederick, MD 21702 USA
    1. Year: 2005
    2. Date: DEC 9
  2. Journal: Molecular Cell
    1. 20
    2. 5
    3. Pages: 658-659
  4. Type of Article: Article
  1. Abstract:

    Two new studies provide in vivo (Kawamoto et al., 2005 [this issue of Molecular Cell]) and in vitro (Mcllwraith et al., 2005 [this issue of Molecular Cell]) evidence that pol eta functions to extend 3' strands exchanged during homologous recombination and raise the issue of how TLS polymerases are selected onto different substrates

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  2. DOI: 10.1016/j.molcel.2005.11.018
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