Skip NavigationSkip to Content
Return Return to Search Results

Chromosomal localization and molecular organization of the human genomic fragment containing the TNF/LT locus in transgenic mice

  1. Author:
    Galimov, A. R.
    Kruglov, A. A.
    Bolsheva, N. L.
    Yurkevich, O. Y.
    Liepinsh, D. J.
    Mufazalov, I. A.
    Kuprash, D. V.
    Nedospasov, S. A.

  2. Author Address

    Galimov, A. R.; Kruglov, A. A.; Bolsheva, N. L.; Yurkevich, O. Yu.; Mufazalov, I. A.; Kuprash, D. V.; Nedospasov, S. A.] Russian Acad Sci, Engelhardt Inst Mol Biol, Moscow 119991, Russia. [Galimov, A. R.; Kruglov, A. A.; Mufazalov, I. A.] Moscow MV Lomonosov State Univ, Fac Bioengn & Bioinformat, Moscow 119899, Russia. [Liepinsh, D. Ja.] NCI, Ctr Canc Res, Frederick, MD 21702 USA. [Nedospasov, S. A.] Moscow MV Lomonosov State Univ, Belozersky Inst Physicochem Biol, Moscow 199992, Russia.
    1. Year: 2008
  2. Journal: Molecular Biology
    1. 42
    2. 4
    3. Pages: 558-566
  4. Type of Article: Article
  1. Abstract:

    The molecular organization, copy number, and chromosome location of the human TNF/LT transgenes were studied in the genomes of two transgenic mouse strains. One strain proved to carry two transgene copies arranged head-to-tail and detected on chromosome 8 by karyotyping. The other strain had one transgene copy observed on chromosome 5. The strains provide a model for studying the physiological functions of the tumor necrosis factor and lymphotoxin.

    See More

  1. Keywords:

External Sources

  1. No sources found.

Library Notes

  1. No notes added.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel