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Ionic liquid mediated synthesis of 5-halouracil nucleosides: key precursors for potential antiviral drugs

  1. Author:
    Kumar, V.
    Malhotra, S. V.
  2. Author Address

    Laboratory of Synthetic Chemistry, SAIC-Frederick, NCI-Frederick, Frederick, Maryland 21702, USA.
    1. Year: 2009
    2. Date: Sep
    3. Epub Date: 2/26/2010
  1. Journal: Nucleosides, nucleotides & nucleic acids
    1. 28
    2. 9
    3. Pages: 821-34
  2. Type of Article: Article
  3. ISSN: 1532-2335 (Electronic);1525-7770 (Linking)
  1. Abstract:

    Synthesis of antiviral 5-halouracil nucleosides, also used as key precursors for the synthesis of other potential antiviral drugs, has been demonstrated using ionic liquids as convenient and efficient reaction medium.

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External Sources

  1. DOI: 10.1080/15257770903170252
  2. PMID: 20183621

Library Notes

  1. Fiscal Year: FY2008-2009
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