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Developmental Biology: Extending the Limb and Body with Vectors and Scalars

  1. Author:
    Lewandoski, M.
    Mackem, S.

  2. Author Address

    [Lewandoski, Mark; Mackem, Susan] NCI, Canc & Dev Biol Lab, Frederick, MD 21702 USA.;Lewandoski, M, NCI, Canc & Dev Biol Lab, Frederick, MD 21702 USA.;lewandom@mail.nih.gov mackems@mail.nih.gov
    1. Year: 2011
    2. Date: Jan
  2. Journal: Current Biology
    1. 21
    2. 1
    3. Pages: R34-R36
  4. Type of Article: Editorial Material
  5. ISSN: 0960-9822
  1. Abstract:

    Outgrowth of the embryonic limb in vertebrates is driven by a proximodistal gradient of cell movement, with WNT and FGF activities controlling direction and velocity, respectively. A similar gradient, though without a directional bias, drives caudal body axis extension.

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External Sources

  1. View Full Text
  2. DOI: 10.1016/j.cub.2010.11.023
  3. View record in Web of Science®
  4. WOS: 000286485200017

Library Notes

  1. Fiscal Year: FY2010-2011
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