Skip NavigationSkip to Content

NCI at Frederick Scientific Publications Advanced Search

Search

  1. NCI-F Publications

  2. Return to Quick Search
Search
  2. Year Published:

Your search returned 33 results.
User Information
Export Records
  1. 1.   Plasma and CNS pharmacokinetics of O(4)-benzylfolic acid (O(4)BF) and metabolite in a non-human primate model
  2. Chuk, M. K.; Cole, D. E.; McCully, C.; Loktionova, N. A.; Pegg, A. E.; Parker, R. J.; Pauly, G.; Widemann, B. C.; Balis, F. M.; Fox, E.
  3. Cancer Chemotherapy and Pharmacology. 2011, Jun; 67(6): 1291-1297.
  1. 2.   In vitro comparison of O4-benzylfolate modulated, BCNU-induced toxicity in human bone marrow using CFU-GM and tumor cell lines
  2. Behrsing, H. P.; Furniss, M. J.; Robillard, K. A.; Tomaszewski, J. E.; Parchment, R. E.
  3. Cancer Chemotherapy and Pharmacology. 2010, May; 65(6): 1083-1091.
  1. 3.   In vitro and in vivo radiosensitization induced by the DNA methylating agent temozolomide
  2. Kil, W. J.; Cerna, D.; Burgan, W. E.; Beam, K.; Carter, D.; Steeg, P. S.; Tofilon, P. J.; Camphausen, K.
  3. Clinical Cancer Research. 2008 14(3): 931-938.
  1. 4.   Substitution of Aminomethyl at the Meta-Position Enhances the Inactivation of O-6-Alkylguanine-DNA Alkyltransferase by O-6-Benzylguanine
  2. Pauly, G. T.; Loktionova, N. A.; Fang, Q. M.; Vankayala, S. L.; Guida, W. C.; Pegg, A. E.
  3. Journal of Medicinal Chemistry. 2008 51(22): 7144-7153.
  1. 5.   Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
  2. Philip, S.; Swaminathan, S.; Kuznetsov, S. G.; Kanugula, S.; Biswas, K.; Chang, S.; Loktionova, N. A.; Haines, D. C.; Kaldis, P.; Pegg, A. E.; Sharant, S. K.
  3. Cancer Research. 2008 68(23): 9973-9981.
  1. 6.   Role of GADD34 in modulation of cisplatin cytotoxicity
  2. Fishel, M. L.; Rabik, C. A.; Bleibel, W. K.; Li, X. M.; Moschel, R. C.; Dolan, M. E.
  3. Biochemical Pharmacology. 2006, JAN 12; 71(3): 239-247.
  1. 7.   Phase I trial of temozolomide plus O-6-benzylguanine for patients with recurrent or progressive malignant glioma
  2. Quinn, J. A.; Desjardins, A.; Weingart, J.; Brem, H.; Dolan, M. E.; Delaney, S. M.; Vredenburgh, J.; Rich, J.; Friedman, A. H.; Reardon, D. A.; Sampson, J. H.; Pegg, A. E.; Moschel, R. C.; Birch, R.; McLendon, R. E.; Provenzale, J. M.; Gururangan, S.; Dancey, J. E.; Maxwell, J.; Tourt-Uhlig, S.; Herndon, J. E.; Bigner, D. D.; Friedman, H. S.
  3. Journal of Clinical Oncology. 2005, OCT 1; 23(28): 7178-7187.
  1. 8.   A bifunctional DNA repair protein from Ferroplasma acidarmanus exhibits O-6-alkylguanine-DNA alkyltransferase and endonuclease V activities
  2. Kanugula, S.; Pauly, G. T.; Moschel, R. C.; Pegg, A. E.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2005, MAR 8; 102(10): 3617-3622.
  1. 9.   Effect of cell cycle inhibition on cisplatin-induced cytotoxicity
  2. Fishel, M. L.; Newell, D. R.; Griffin, R. J.; Davison, R.; Wang, L. Z.; Curtin, N. J.; Zuhowski, E. G.; Kasza, K.; Egorin, M. J.; Moschel, R. C.; Dolan, M. E.
  3. Journal of Pharmacology and Experimental Therapeutics. 2005, JAN; 312(1): 206-213.
  1. 10.   Intra- and intercellular variations in the repair efficiency of O-6-methylguanine, and their contribution to kinetic complexity
  2. Souliotis, V. L.; Sfikakis, P. P.; Anderson, L. M.; Kyrtopoulos, S. A.
  3. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis. 2004, DEC 21; 568(2): 155-170.
  1. 11.   Brain tumor cell lines resistant to O-6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O-6 -alkylguanine-DNA alkyltransferase mutations
  2. Bacolod, M. D.; Johnson, S. P.; Pegg, A. E.; Dolan, M. E.; Moschel, R. C.; Bullock, N. S.; Fang, Q. M.; Colvin, O. M.; Modrich, P.; Bigner, D. D.; Friedman, H. S.
  3. Molecular Cancer Therapeutics. 2004, SEP; 3(9): 1127-1135.
  1. 12.   2-amino-O-4-benzylpteridines and O-4-benzylfolic acid: Potent inactivators of O-6-alkylguanine-DNA alkyltransferase and potential chemotherapy adjuvants
  2. Nelson, M. E.; Loktionova, N.; Pegg, A. E.; Moschel, R. C.
  3. Abstracts of Papers of the American Chemical Society. 2004, AUG 22; 228(Part 1): 110-MEDI, Abstract U927-110-MEDI, Abstract U927.
  1. 13.   The repair of the tobacco specific nitrosamine derived adduct O-6-[4-oxo-4-(3-pyridyl)butyl]guanine by O-6-alkylguanine-DNA alkyltransferase variants
  2. Mijal, R. S.; Thomson, N. M.; Fleischer, N. L.; Pauly, G. T.; Moschel, R. C.; Kanugula, S.; Fang, Q. M.; Pegg, A. E.; Peterson, L. A.
  3. Chemical Research in Toxicology. 2004 17(3): 424-434.
  1. 14.   Enhancement of platinum-induced cytotoxicity by O-6- Benzylguanine
  2. Fishel, M. L.; Delaney, S. M.; Friesen, L. D.; Hansen, R. J.; Zuhowski, E. G.; Moschel, R. C.; Egorin, M. J.; Dolan, M. E.
  3. Molecular Cancer Therapeutics. 2003 2(7): 633-640.
  1. 15.   O-6-benzylguanine-mediated enhancement of chemotherapy
  2. Friedman, H. S.; Keir, S.; Pegg, A. E.; Houghton, P. J.; Colvin, O. M.; Moschel, R. C.; Bigner, D. D.; Dolan, M. E.
  3. Molecular Cancer Therapeutics. 2002 1(11): 943-948.
  1. 16.   Mutagenesis by O-6- 4-oxo-4-(3-pyridyl)butyl guanine in Escherichia coli and human cells
  2. Pauly, G. T.; Peterson, L. A.; Moschel, R. C.
  3. Chemical Research in Toxicology. 2002 15(2): 165-169.
  1. 17.   Phase II trial of carmustine plus O-6-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma
  2. Quinn, J. A.; Pluda, J.; Dolan, M. E.; Delaney, S.; Kaplan, R.; Rich, J. N.; Friedman, A. H.; Reardon, D. A.; Sampson, J. H.; Colvin, O. M.; Haglund, M. M.; Pegg, A. E.; Moschel, R. C.; McLendon, R. E.; Provenzale, J. M.; Gururangan, S.; Tourt-Uhlig, S.; Herndon, J. E.; Bigner, D. D.; Friedman, H. S.
  3. Journal of Clinical Oncology. 2002 20(9): 2277-2283.
  1. 18.   DNA adducts and liver DNA replication in rats during chronic exposure to N-nitrosodimethylamine (NDMA) and their relationships to the dose-dependence of NDMA hepatocarcinogenesis
  2. Souliotis, V. L.; Henneman, J. R.; Reed, C. D.; Chhabra, S. K.; Diwan, B. A.; Anderson, L. M.; Kyrtopoulos, S. A.
  3. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis. 2002 500(1-2): 75-87.
  1. 19.   Debenzylation of O-6-benzyl-8-oxoguanine in human liver: implications for O-6-benzylguanine metabolism
  2. Long, L.; Moschel, R. C.; Dolan, M. E.
  3. Biochemical Pharmacology. 2001 61(6): 721-726.
  1. 20.   Inactivation of O-6-alkylguanine-DNA alkyltransferase by 8- substituted O-6-benzylguanine analogs in mice
  2. Ewesuedo, R. B.; Wilson, L. R.; Friedman, H. S.; Moschel, R. C.; Dolan, M. E.
  3. Cancer Chemotherapy and Pharmacology. 2001 47(1): 63-69.
  1. 21.   Phase I trial of carmustine plus O-6-benzylguanine for patients with recurrent or progressive malignant glioma
  2. Friedman, H. S.; Pluda, J.; Quinn, J. A.; Ewesuedo, R. B.; Long, L.; Friedman, A. H.; Cokgor, I.; Colvin, O. M.; Haglund, M. M.; Ashley, D. M.; Rich, J. N.; Sampson, J.; Pegg, A. E.; Moschel, R. C.; McLendon, R. E.; Provenzale, J. M.; Stewart, E. S.; Tourt-Uhlig, S.; Garcia-Turner, A. M.; Herndon, J. E.; Bigner, D. D.; Dolan, M. E.
  3. Journal of Clinical Oncology. 2000 18(20): 3522-3528.
  1. 22.   Plasma and cerebrospinal fluid pharmacokinetics of O-6- benzylguanine and analogues in nonhuman primates
  2. Long, L.; Berg, S. L.; Roy, S. K.; McCully, C. L.; Song-Yoo, H. W.; Moschel, R. C.; Balis, F. M.; Dolan, M. E.
  3. Clinical Cancer Research. 2000 6(9): 3662-3669.
  1. 23.   O-6-benzylguanine-mediated enhancement of nitrosourea activity in Mer(-) central nervous system tumor xenografts - implications for clinical trials
  2. Keir, S. T.; Dolan, M. E.; Pegg, A. E.; Lawless, A.; Moschel, R. C.; Bigner, D. D.; Friedman, H. S.
  3. Cancer Chemotherapy and Pharmacology. 2000 45(6): 437-440.
  1. 24.   Potentiation of BCNU antitumor efficacy by 9-substituted O-6-benzylguanines. Effect of metabolism
  2. Kokkinakis, D. M.; Moschel, R. C.; Pegg, A. E.; Schold, S. C.
  3. Cancer Chemotherapy and Pharmacology. 2000 45(1): 69-77.
  1. 25.   Coexposure to ethanol with N-nitrosodimethylamine or 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone during lactation of rats: Marked increase in O-6-methylguanine-DNA adducts in maternal mammary gland and in suckling lung and kidney
  2. Chhabra, S. K.; Anderson, L. M.; Perella, C.; Desai, D.; Amin, S.; Kyrtopoulos, S. A.; Souliotis, V. L.
  3. Toxicology and Applied Pharmacology. 2000 169(2): 191-200.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel