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  1. 1.   Beyond traditional screening: Unveiling antibiotic potentials of actinomycetes in extreme environments
  2. Trenozhnikova, Lyudmila P; Baimakhanova, Gul B; Baimakhanova, Baiken B; Balgimbayeva, Assya S; Daugaliyeva, Saule T; Faizulina, Elmira R; Tatarkina, Larisa G; Spankulova, Gulzhan A; Berillo, Dmitriy A; Beutler,John
  3. Heliyon. 2024, Nov 30; 10(22): e40371.
  1. 2.   The effect of modulation of gut microbiome profile on radiation-induced carcinogenesis and survival
  2. Cook, John A; Sowers, Anastasia L; Choudhuri, Rajani; Gadisetti, Chandramouli; Edmondson,Elijah; Gohain, Sangeeta; Krishna, Murali C; Mitchell, James B
  3. Journal of Radiation Research. 2022, Oct 17;
  1. 3.   Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy.
  2. Namasivayam, Sivaranjani; Maiga, Mamoudou; Yuan, Wuxing; Thovarai, Vishal; Costa, Diego L; Mittereder, Lara R; Wipperman, Matthew F; Glickman, Michael S; Dzutsev, Amiran; Trinchieri, Giorgio; Sher, Alan
  3. Microbiome. 2017, Jul 07; 5(1): 71.
  1. 4.   Synergistic Interaction of the Triple Combination of Amphotericin B, Ciprofloxacin, and Polymorphonuclear Neutrophils against Aspergillus fumigatus
  2. Stergiopoulou, T.; Meletiadis, J.; Sein, T.; Papaioannidou, P.; Walsh, T. J.; Roilides, E.
  3. Antimicrobial Agents and Chemotherapy. 2011, Dec; 55(12): 5923-5929.
  1. 5.   Synthesis and Anticancer Activity of 13-Membered Cyclic Enediynes
  2. Sharma, M.; Joshi, M. C.; Kumar, V.; Malhotra, S. V.; Rawat, D. S.
  3. Archiv Der Pharmazie. 2011, Sep; 344(9): 564-571.
  1. 6.   Synthesis and Biological Evaluation of ABCD Ring Fragments of the Kibdelones
  2. Sloman, D. L.; Mitasev, B.; Scully, S. S.; Beutler, J. A.; Porco, J. A.
  3. Angewandte Chemie-International Edition. 2011, Mar 7; 50(11): 2511-2515.
  1. 7.   Substituted E-3-(3-Indolylmethylene)-1,3-dihydroindo1-2-ones with Antitumor Activity. In Depth Study of the Effect on Growth of Breast Cancer Cells
  2. Andreani, A.; Bellini, S.; Burnelli, S.; Granaiola, M.; Leoni, A.; Locatelli, A.; Morigi, R.; Rambaldi, M.; Varoli, L.; Calonghi, N.; Cappadone, C.; Zini, M.; Stefanelli, C.; Masotti, L.; Shoemaker, R. H.
  3. Journal of Medicinal Chemistry. 2010, Aug; 53(15): 5567-5575.
  1. 8.   Natural product scaffolds as leads-to drugs
  2. Newman, D. J.; Cragg, G. M.
  3. Future Medicinal Chemistry. 2009, Nov; 1(8): 1415-1427.
  1. 9.   ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC
  2. Stockwin, L. H.; Yu, S. X.; Stotler, H.; Hollingshead, M. G.; Newton, D. L.
  3. Bmc Cancer. 2009 9(63): 1-13.
  1. 10.   Madurahydroxylactone derivatives as dual inhibitors of human immunodeficiency virus type 1 integrase and RNase H
  2. March, C.; Beutler, J. A.; Wamiru, A.; Budihas, S.; Mollmann, U.; Heinisch, L.; Mellors, J. W.; Le Grice, S. F.; Pommier, Y.
  3. Antimicrobial Agents and Chemotherapy. 2008 52(1): 361-364.
  1. 11.   Crystal structures of human alpha-defensins HNP4, HD5, and HD6
  2. Szyk, A.; Wu, Z. B.; Tucker, K.; Yang, D.; Lu, W. Y.; Lubkowski, J.
  3. Protein Science. 2006, Dec; 15(12): 2749-2760.
  1. 12.   Human beta-defensins
  2. Pazgier, M.; Hoover, D. M.; Yang, D.; Lu, W.; Lubkowski, J.
  3. Cellular and Molecular Life Sciences. 2006, Jun; 63(11): 1294-1313.
  1. 13.   Broad spectrum antimicrobial activity of leukocyte extracts from the American alligator (Alligator mississipiensis)
  2. Merchant, M. E.; Leger, N.; Jerkins, E.; Mills, K.; Pallansch, M. B.; Paulman, R. L.; Ptak, R. G.
  3. Veterinary Immunology and Immunopathology. 2006, Apr; 110(3-4): 221-228.
  1. 14.   International collaboration in drug discovery and development from natural sources
  2. Cragg, G. M.; Newman, D. J.
  3. Pure and Applied Chemistry. 2005, NOV; 77(11): 1923-1942.
  1. 15.   Cross-resistance of Escherichia coli RNA polymerases conferring rifarnpin resistance to different antibiotics
  2. Xu, M.; Zhou, Y. N.; Goldstein, B. P.; Jin, D. J.
  3. Journal of Bacteriology. 2005, APR; 187(8): 2783-2792.
  1. 16.   Detection of galactomannan antigenemia in patients receiving piperacillin-tazobactam and correlations between in vitro, in vivo, and clinical properties of the drug-antigen interaction
  2. Walsh, T. J.; Shoham, S.; Petraitiene, R.; Sein, T.; Schaufele, R.; Kelaher, A.; Murray, H.; Mya-San, C.; Bacher, J.; Petraitis, V.
  3. Journal of Clinical Microbiology. 2004, OCT; 42(10): 4744-4748.
  1. 17.   From pro defensins to defensins: synthesis and characterization of human neutrophil pro alpha-defensin-1 and its mature domain
  2. Wu, Z.; Prahl, A.; Powell, R.; Ericksen, B.; Lubkowski, J.; Lu, W.
  3. Journal of Peptide Research. 2003 62(2): 53-62.
  1. 18.   Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3
  2. Wu, Z. B.; Hoover, D. M.; Yang, D.; Boulegue, C.; Santamaria, F.; Oppenheim, J. J.; Lubkowski, J.; Lu, W. Y.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2003 100(15): 8880-8885.
  1. 19.   The structure of human beta-defensin-1 - New insights into structural properties of beta-defensins
  2. Hoover, D. M.; Chertov, O.; Lubkowski, J.
  3. Journal of Biological Chemistry. 2001 276(42): 39021-39026.
  1. 20.   The influence of natural products upon drug discovery
  2. Newman, D. J.; Cragg, G. M.; Snader, K. M.
  3. Natural Product Reports. 2000 17(3): 215-234.
  1. 21.   A Molecular Modeling Study of Antibiotics-Rna Interactions - Application to Hiv-1 Rev Response Element
  2. Pramodh, V.; Pattabiraman, N.; Le, S. Y.; Maizel, J. V.
  3. Theochem-Journal of Molecular Structure. 1998 423(1-2): 125-136.
  1. 22.   Polycyclic aromatic hydrocarbons: Stealth carcinogens?
  2. Khan, Q. A.; Vousden, K.; Dipple, A.
  3. Annual Meeting of the American Association for Cancer Research. 1997, 38 A4287.
  1. 23.   KRN 5500 selectively disrupts the Golgi apparatus in HT-29 colon carcinoma cells
  2. Kamishohara, M.; Kenney, S.; Vistica, D.; Sausville, E.
  3. Annual Meeting of the American Association for Cancer Research. 1997, 38 A1528.
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