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  1. 1.   SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck
  2. Nigam, Nupur; Bernard, Benjamin; Sevilla, Samantha; Kim, Sohyoung; Dar, Mohd Saleem; Tsai, Daniel; Robbins, Yvette; Burkitt, Kyunghee; Sievers, Cem; Allen, Clint T; Bennett, Richard L; Tettey, Theophilus T; Carter, Benjamin; Rinaldi, Lorenzo; Lingen, Mark W; Sater, Houssein; Edmondson, Elijah F; Moshiri, Arfa; Saeed, Abbas; Cheng, Hui; Luo, Xiaolin; Brennan, Kevin; Koparde, Vishal; Chen, Chen; Das, Sudipto; Andresson,Thorkell; Abdelmaksoud,Abdalla; Murali, Madhavi; Sakata, Seiji; Takeuchi, Kengo; Chari,Raj; Nakamura, Yusuke; Uppaluri, Ravindra; Sunwoo, John B; Van Waes, Carter; Licht, Jonathan D; Hager, Gordon L; Saloura, Vassiliki
  3. Cell Reports. 2023, Jul 17; 42(7): 112823.
  1. 2.   Identification of pyrrolo[3',4':3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas
  2. Barreca, Marilia; Spanò, Virginia; Rocca, Roberta; Bivacqua, Roberta; Gualtieri, Gianmarco; Raimondi, Maria Valeria; Gaudio, Eugenio; Bortolozzi, Roberta; Manfreda, Lorenzo; Bai,Ruoli; Montalbano, Alessandra; Alcaro, Stefano; Hamel,Ernest; Bertoni, Francesco; Viola, Giampietro; Barraja, Paola
  3. European Journal of Medicinal Chemistry. 2023, Apr 12; 254: 115372.
  1. 3.   Anti-TNFR2 enhanced the antitumor activity of a new HMGN1/3M-052 stimulated dendritic cell vaccine in a mouse model of colon cancer
  2. Zhu, Lan; Zhang, Xiangyan; Chen, Xin; Yang,De; Nie, Yujie; Pan, Runsang; Li, Linzhao; Wang, Chenglv; Gui, Huan; Chen, Shuanghui; Jing, Qianyu; Wang, Mengjiao; Nie, Yingjie
  3. Biochemical and Biophysical Research Communications. 2023, Feb 16; 653: 106-114.
  1. 4.   Restoration of microRNA metabolism trigger robust antitumor responses
  2. Bofill De Ros,Xavier
  3. Molecular Therapy. Nucleic Acids. 2022, Sep 13; 29: 498-500.
  1. 5.   Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities
  2. Romagnoli, Romeo; Oliva, Paola; Prencipe, Filippo; Manfredini, Stefano; Budassi, Federica; Brancale, Andrea; Ferla, Salvatore; Hamel,Ernest; Corallo, Diana; Aveic, Sanja; Manfreda, Lorenzo; Mariotto, Elena; Bortolozzi, Roberta; Viola, Giampietro
  3. Pharmaceuticals (Basel, Switzerland). 2022, Aug 21; 15(8):
  1. 6.   GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity
  2. Heitzeneder, Sabine; Bosse, Kristopher R.; Zhu, Zhongyu; Zhelev, Doncho; Majzner, Robbie G.; Radosevich, Molly T.; Dhingra, Shaurya; Sotillo, Elena; Buongervino, Samantha; Pascual-Pasto, Guillem; Garrigan, Emily; Xu, Peng; Huang, Jing; Salzer, Benjamin; Delaidelli, Alberto; Raman, Swetha; Cui, Hong; Martinez, Benjamin; Bornheimer, Scott J.; Sahaf, Bita; Alag, Anya; Fetahu, Irfete S.; Hasselblatt, Martin; Parker, Kevin R.; Anbunathan, Hima; Hwang, Jennifer; Huang, Min; Sakamoto, Kathleen; Lacayo, Norman J.; Klysz, Dorota D.; Theruvath, Johanna; Vilches-Moure, Jose G.; Satpathy, Ansuman T.; Chang, Howard Y.; Lehner, Manfred; Taschner-Mandl, Sabine; Julien, Jean-Phillipe; Sorensen, Poul H.; Dimitrov, Dimiter S.; Maris, John M.; Mackall, Crystal L.
  3. Cancer Cell. 2022, Jan 10; 40(1): 53-+.
  1. 7.   A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer
  2. Jiang, Mengmeng; Liu,Jia; Yang,De; Tross,Debra; Li, Ping; Chen, Fengyang; Alam,Md Masud; Faustman, Denise L; Oppenheim,Joost; Chen, Xin
  3. International immunopharmacology. 2021, Nov 15; 101(Pt A): 108345.
  1. 8.   CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice
  2. Li, Nan; Torres, Madeline B.; Spetz, Madeline R.; Wang, Ruixue; Peng, Luyi; Tian, Meijie; Dower, Christopher M.; Nguyen, Rosa; Sun, Ming; Tai, Chin-Hsien; de Val, Natalia; Cachau,Raul; Wu, Xiaolin; Hewitt, Stephen M.; Kaplan, Rosandra N.; Khan, Javed; St Croix,Brad; Thiele, Carol J.; Ho, Mitchell
  3. Cell reports. Medicine. 2021, Jun 15; 2(6):
  1. 9.   The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity
  2. Xiang, Weiguo; Quadery, Tasdique M; Hamel,Ernest; Luckett-Chastain, Lerin R; Ihnat, Michael A; Mooberry, Susan L; Gangjee, Aleem
  3. Bioorganic & medicinal chemistry. 2021, Jan 1; 29: 115887.
  1. 10.   A novel patient-derived orthotopic xenograft (PDOX) mouse model of highly-aggressive liver metastasis for identification of candidate effective drug-combinations
  2. Zhang, Zhiying; Hu, Kaiwen; Miyake, Kentaro; Kiyuna, Tasuku; Oshiro, Hiromichi; Wangsiricharoen, Sintawat; Kawaguchi, Kei; Higuchi, Takashi; Razmjooei, Sahar; Miyake, Masuyo; Chawla, Sant P; Singh,Shree Ram; Hoffman, Robert M
  3. Scientific reports. 2020, Nov 18; 10(1): 20105.
  1. 11.   Chemically Programmable and Switchable CAR-T Therapy
  2. Qi, Junpeng; Tsuji, Kohei; Hymel, David; Burke,Terrence; Hudecek, Michael; Rader, Christoph; Peng, Haiyong
  3. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2020, MAY 18;
  1. 12.   Mesothelin enhances tumor vascularity in newly forming pancreatic peritoneal metastases
  2. Avula, Leela Rani; Rudloff, Michael; El-Behaedi, Salma; Arons, Danielle; Albalawy, Rakan; Chen,Jack; Zhang, Xianyu; Alewine, Christine
  3. Molecular cancer research : MCR. 2020, FEB; 18(2): 229-239.
  1. 13.   PDE6D Inhibitors with a New Design Principle Selectively Block K-Ras Activity
  2. Siddiqui, Farid A; Alam, Catharina; Rosenqvist, Petja; Ora, Mikko; Sabt, Ahmed; Manoharan, Ganesh Babu; Bindu,Lakshman; Okutachi, Sunday; Catillon, Marie; Taylor,Troy; Abdelhafez, Omaima M; Lönnberg, Harri; Stephen,Andy; Papageorgiou, Anastassios C; Virta, Pasi; Abankwa, Daniel
  3. ACS omega. 2020, Jan 14; 5(1): 832-842.
  1. 14.   IL15 by Continuous Intravenous Infusion to Adult Patients with Solid Tumors in a Phase I Trial Induced Dramatic NK-Cell Subset Expansion
  2. Conlon, Kevin C.; Potter, E. Lake; Pittaluga, Stefania; Lee, Chyi-Chia Richard; Miljkovic, Milos D.; Fleisher, Thomas A.; Dubois, Sigrid; Bryant, Bonita R.; Petrus, Michael; Perera, Liyanage P.; Hsu, Jennifer; Figg, William D.; Peer, Cody J.; Shih, Joanna H.; Yovandich,Jason; Creekmore,Stephen; Roederer, Mario; Waldmann, Thomas A.
  3. CLINICAL CANCER RESEARCH. 2019, Aug 15; 25(16): 4945-4954.
  1. 15.   Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents
  2. Morigi, Rita; Locatelli, Alessandra; Leoni, Alberto; Rambaldi, Mirella; Bortolozzi, Roberta; Mattiuzzo, Elena; Ronca, Roberto; Maccarinelli, Federica; Hamel,Ernest; Bai,Ruoli; Brancale, Andrea; Viola, Giampietro
  3. European journal of medicinal chemistry. 2019, MAR 15; 166: 514-530.
  1. 16.   Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy
  2. Tietze, J. K.; Wilkins, D. E. C.; Sckisel, G. D.; Bouchlaka, M. N.; Alderson, K. L.; Weiss, J. M.; Ames, E.; Bruhn, K. W.; Craft, N.; Wiltrout, R. H.; Longo, D. L.; Lanier, L. L.; Blazar, B. R.; Redelman, D.; Murphy, W. J.
  3. Blood. 2012, Mar; 119(13): 3073-3083.
  1. 17.   Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
  2. Newman, D. J.; Cragg, G. M.
  3. Journal of Natural Products. 2012, Mar; 75(3): 311-335.
  1. 18.   Vascular endothelial growth factor receptor 2 inhibition in-vivo affects tumor vasculature in a tumor type-dependent way and downregulates vascular endothelial growth factor receptor 2 protein without a prominent role for miR-296
  2. Langenkamp, E.; Zwiers, P. J.; Moorlag, H. E.; Leenders, W. P.; Croix, B. S.; Molema, G.
  3. Anti-Cancer Drugs. 2012, Feb; 23(2): 161-172.
  1. 19.   Intratumoral Injection of CpG Oligonucleotides Induces the Differentiation and Reduces the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells
  2. Shirota, Y.; Shirota, H.; Klinman, D. M.
  3. Journal of Immunology. 2012, Feb; 188(4): 1592-1599.
  1. 20.   Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors
  2. Leese, M. P.; Jourdan, F.; Dohle, W.; Kimberley, M. R.; Thomas, M. P.; Bai, R. L.; Hamel, E.; Ferrandis, E.; Potter, B. V. L.
  3. Acs Medicinal Chemistry Letters. 2012, Jan; 3(1): 5-9.
  1. 21.   Cyclostreptin Derivatives Specifically Target Cellular Tubulin and Further Map the Paclitaxel Site
  2. Calvo, E.; Barasoain, I.; Matesanz, R.; Pera, B.; Camafeita, E.; Pineda, O.; Hamel, E.; Vanderwal, C. D.; Andreu, J. M.; Lopez, J. A.; Diaz, J. F.
  3. Biochemistry. 2012, Jan; 51(1): 329-341.
  1. 22.   IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors
  2. Kerkar, S. P.; Goldszmid, R. S.; Muranski, P.; Chinnasamy, D.; Yu, Z. Y.; Reger, R. N.; Leonardi, A. J.; Morgan, R. A.; Wang, E.; Marincola, F. M.; Trinchieri, G.; Rosenberg, S. A.; Restifo, N. P.
  3. Journal of Clinical Investigation. 2011, Dec; 121(12): 4746-4757.
  1. 23.   DNA intercalator korkormicin A preferentially kills tumor cells expressing wild type p53
  2. Kitagaki, J.; Yang, Y. L.
  3. Biochemical and Biophysical Research Communications. 2011, Oct; 414(1): 186-191.
  1. 24.   Gut microbiota and probiotics in colon tumorigenesis
  2. Zhu, Y. M.; Luo, T. M.; Jobin, C.; Young, H. A.
  3. Cancer Letters. 2011, Oct; 309(2): 119-127.
  1. 25.   Synthetic and Application Perspectives of Azapodophyllotoxins: Alternative Scaffolds of Podophyllotoxin
  2. Kumar, A.; Kumar, V.; Alegria, A. E.; Malhotra, S. V.
  3. Current Medicinal Chemistry. 2011, Sep; 18(25): 3853-3870.
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